Protein Info for IAI47_21625 in Pantoea sp. MT58

Annotation: UDP-4-amino-4-deoxy-L-arabinose aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 378 PF01041: DegT_DnrJ_EryC1" amino acids 12 to 372 (361 residues), 419.6 bits, see alignment E=1.8e-129 PF00155: Aminotran_1_2" amino acids 35 to 161 (127 residues), 30.6 bits, see alignment E=3.2e-11 PF01053: Cys_Met_Meta_PP" amino acids 36 to 216 (181 residues), 27.4 bits, see alignment E=1.9e-10

Best Hits

Swiss-Prot: 72% identical to ARNB_ESCF3: UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase (arnB) from Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)

KEGG orthology group: K07806, UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase [EC: 2.6.1.87] (inferred from 96% identity to pva:Pvag_pPag10072)

MetaCyc: 72% identical to UDP-4-amino-4-deoxy-L-arabinose aminotransferase (Escherichia coli K-12 substr. MG1655)
RXN0-1863 [EC: 2.6.1.87, 2.6.1.92]

Predicted SEED Role

"UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase (EC 2.6.1.-)" in subsystem Lipid A-Ara4N pathway ( Polymyxin resistance ) (EC 2.6.1.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.-

Use Curated BLAST to search for 2.6.1.- or 2.6.1.87 or 2.6.1.92

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (378 amino acids)

>IAI47_21625 UDP-4-amino-4-deoxy-L-arabinose aminotransferase (Pantoea sp. MT58)
MDFLPFSRPSFGDEELAAVKAVFDSGWITTGAKCAELEQAFVQLTGNQHAIAVSSATAGM
HVTLMAMGIGPGDEVITPSMTWVSTLNLITLLGATPVMIDVDPDNLMVTPELIAQAITSR
TRAIIPVHYAGAPADLTPIYQLAEQHGIAIIEDAAHAVGTTYHEKPIGHRGTAIFSFHAI
KNITCAEGGLVVTDDAALADRIRSLKFHGLAVDAFDRQTKGRLPQAEVMMPGFKYNLPDI
SAAIALVQLQKLPGFIARRREIAERYLEALHTLPFTPLSLPAWPHQHAWHLFIIRIDEQR
CGLTRDAFMQALKSRDIGSGLHFRAAHTHKYYREHYPDLRLPASELNSQQMCSIPLFPSM
TDQDIERVIQALHDIAGA