Protein Info for IAI47_21335 in Pantoea sp. MT58

Annotation: RepB family plasmid replication initiator protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 357 PF01051: Rep3_N" amino acids 116 to 224 (109 residues), 44.5 bits, see alignment E=1.1e-15

Best Hits

Swiss-Prot: 78% identical to REPA_SALTI: Replication protein RepA (repA) from Salmonella typhi

KEGG orthology group: None (inferred from 95% identity to pva:Pvag_pPag10161)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (357 amino acids)

>IAI47_21335 RepB family plasmid replication initiator protein (Pantoea sp. MT58)
MPRKEPDILNIADAFSETDKRTGEVVTLTPNSNNTVQPVALMRLGLFVPTLKSTARSQKN
QMNAMDVTQDLKQLSLVRSEGYDNIKILGARLDMDNDFKTWVGIIRAFATHECLGDTVTL
SFVEFAKLCGIPSVRLSSKLRSRLDASLTRIASNTLTFTSKGGENYTTHLVQSAKYSIKK
DTVTLQADPKIFELYQFDRKVLLQLKAINELARKESAQALYTFIESLPPKPAPISMARLR
ARLNLTSRVITQNATVRKAMEQLKEIGYLDYTETRRGSSVYFWVHYRHPKLRPAELPLSN
SDLIDDEIDDYDDLDLDPGVIDVSLPEPMIEEENSELVMVSREEKELLNKIRKQKKL