Protein Info for IAI47_21075 in Pantoea sp. MT58

Annotation: tryptophan permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 414 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 40 to 62 (23 residues), see Phobius details amino acids 90 to 111 (22 residues), see Phobius details amino acids 132 to 150 (19 residues), see Phobius details amino acids 158 to 178 (21 residues), see Phobius details amino acids 192 to 216 (25 residues), see Phobius details amino acids 228 to 247 (20 residues), see Phobius details amino acids 285 to 310 (26 residues), see Phobius details amino acids 322 to 342 (21 residues), see Phobius details amino acids 348 to 367 (20 residues), see Phobius details amino acids 387 to 405 (19 residues), see Phobius details PF03222: Trp_Tyr_perm" amino acids 10 to 401 (392 residues), 374.6 bits, see alignment E=3.4e-116 TIGR00837: aromatic amino acid transport protein" amino acids 15 to 395 (381 residues), 384.3 bits, see alignment E=3.9e-119

Best Hits

KEGG orthology group: K03835, tryptophan-specific transport protein (inferred from 47% identity to eta:ETA_23270)

Predicted SEED Role

"Tryptophan-specific transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (414 amino acids)

>IAI47_21075 tryptophan permease (Pantoea sp. MT58)
MSDIAISRRSPSVFWGATIICGTVVGAGMFVLPVVMAGAWFGWALLILTFSWVCMLISGL
MFHRVSQHYPLETGYDKIVRDVLGRNWAEVNGLSLVFVLGILTYAYISAVGPVYDHSLSR
LTGKTVSSSEAKVMLSLTVAAIVWLGTSSIGRIMSVLLITKIVLLLILFGGLLTTVNVDY
LLDSQNSAASYWPYMLGIVPFCLASFGYHGNISGLISYYNGDHRRVKICLYTGTAVALVI
YLFWIICTMGNLPRSAFPEIASQGGDIAALMHAFSLRGYTAGMSLLFSIFSHFAVICSFV
GVTAGLVDYISDRLTLPRTRTGRLKATAITFLPPLSLSLLFPDGFVSAIGYAGLIATIWA
VIVPGLLHLKMRSLHYSGYQRSQWDGLQLCMIMVFAALNILSWALREFDLLPVF