Protein Info for IAI47_20825 in Pantoea sp. MT58
Annotation: phenylacetate--CoA ligase family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
No protein families (PFam or TIGRFam), signal peptides, or transmembrane helices were found in this protein.
Best Hits
KEGG orthology group: K01912, phenylacetate-CoA ligase [EC: 6.2.1.30] (inferred from 80% identity to epy:EpC_14360)Predicted SEED Role
"Phenylacetate-coenzyme A ligase (EC 6.2.1.30)" in subsystem Aromatic amino acid interconversions with aryl acids (EC 6.2.1.30)
MetaCyc Pathways
- penicillin G and penicillin V biosynthesis (1/4 steps found)
- phenylacetate degradation II (anaerobic) (1/4 steps found)
- L-phenylalanine degradation IV (mammalian, via side chain) (4/9 steps found)
- phenylacetate degradation I (aerobic) (3/9 steps found)
- superpathway of phenylethylamine degradation (4/11 steps found)
- anaerobic aromatic compound degradation (Thauera aromatica) (3/27 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 6.2.1.30
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (469 amino acids)
>IAI47_20825 phenylacetate--CoA ligase family protein (Pantoea sp. MT58) MYAIFKERVIAQAKEVYYLHSAFHAGNISLNELGLHQNNKLREVVKYVAEHSPFYREHFK GLTSFDIESLTTAGLTSLPFTTKDDLRMQGAALASAPLHQSWIYYETTGTTGKPTPCPRN ETDSVHNNTPLIIHYRNIFEQIAPHHVVGVMGPTELHSTGDTFEDVFRSLGYSVVKMWPR SPVVGMKRVMALINELQITALVCTPAVAIAVARFIKDSGGDPSATSVKLILTVGELTTPP LLRNIGEIWGAKVYSCMYASQESSILAVCAQDSHLYTVPLNNYYEIINPFSGAACDITTG QGVGELVITHLYKGQKPLIRYRTGDMVRSTLMPDGSQKIVPIGRVRDVLTLNGQAYCAWD LEAALLEKLEGCLDYAIQIDNREGRDVLNITVEMFNRQADVSSLLSNVKRHIEQNIAGVS IHLIDGETSRVTGTSAMVSWKAARIHDLRPAADNSDRDAALALINRGFE