Protein Info for IAI47_20330 in Pantoea sp. MT58

Annotation: LacI family DNA-binding transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00356: LacI" amino acids 3 to 47 (45 residues), 63.9 bits, see alignment 1.9e-21 PF00532: Peripla_BP_1" amino acids 60 to 316 (257 residues), 91.3 bits, see alignment E=1.6e-29 PF13407: Peripla_BP_4" amino acids 61 to 302 (242 residues), 71.4 bits, see alignment E=1.8e-23 PF13377: Peripla_BP_3" amino acids 166 to 326 (161 residues), 128.8 bits, see alignment E=4.5e-41

Best Hits

KEGG orthology group: None (inferred from 87% identity to pva:Pvag_pPag30254)

Predicted SEED Role

"Ribose operon repressor" in subsystem D-ribose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (326 amino acids)

>IAI47_20330 LacI family DNA-binding transcriptional regulator (Pantoea sp. MT58)
MSIQRIALMAGVSVATVSRVLNNSDSVKPANRQKVLAAIEESNYQPNLLARQLRTARSSM
ILVLVSDISNPFCAEVVKGIEEQAEKNGYRILLCNSGADIARSRSSLQLLSGKMVDGIIT
MDAFSKLPELSQLIGSAPWVQCAEHDDNGQISCVGIDDEAAAQSVVHYLARQGRKRIALI
NHDLSYRYARLRQQGYTTELDEQQLSWQAIAYASALSFSAGKAAMNQLLAAESRPDAVFA
VCDTLAAGAMAAIQQAGLRIPQDFALVGFDGSELASMVSPPLTTLAQPSKEIGRRACELV
LQKIAWPDAPPQSVIMQGELVVRASS