Protein Info for IAI47_20270 in Pantoea sp. MT58

Annotation: formate dehydrogenase subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 990 PF13510: Fer2_4" amino acids 7 to 76 (70 residues), 38.2 bits, see alignment 5.4e-13 PF10588: NADH-G_4Fe-4S_3" amino acids 89 to 121 (33 residues), 31.1 bits, see alignment (E = 6.2e-11) PF13237: Fer4_10" amino acids 143 to 203 (61 residues), 26.1 bits, see alignment 3.2e-09 PF00037: Fer4" amino acids 143 to 160 (18 residues), 23.7 bits, see alignment (E = 1.4e-08) PF12838: Fer4_7" amino acids 148 to 206 (59 residues), 30.5 bits, see alignment 1.9e-10 PF04879: Molybdop_Fe4S4" amino acids 262 to 315 (54 residues), 68.8 bits, see alignment 1.4e-22 TIGR01591: formate dehydrogenase, alpha subunit" amino acids 266 to 937 (672 residues), 806.8 bits, see alignment E=6.3e-247 PF00384: Molybdopterin" amino acids 318 to 744 (427 residues), 257.2 bits, see alignment E=1.1e-79 PF01568: Molydop_binding" amino acids 829 to 934 (106 residues), 85.7 bits, see alignment E=1e-27

Best Hits

Swiss-Prot: 54% identical to YJGC_BACSU: Probable oxidoreductase YjgC (yjgC) from Bacillus subtilis (strain 168)

KEGG orthology group: K00123, formate dehydrogenase, alpha subunit [EC: 1.2.1.2] (inferred from 94% identity to pva:Pvag_pPag30267)

Predicted SEED Role

"Oxidoreductase alpha (Molybdopterin) subunit"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.2.1.2

Use Curated BLAST to search for 1.2.1.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (990 amino acids)

>IAI47_20270 formate dehydrogenase subunit alpha (Pantoea sp. MT58)
MSENYCTILFNGERLKGLANQPLIDFLDAHGKKLPHVCYHPALPPLQSCDVCWVDANGER
VRGCTLRTEEGLSVQSEGTALRAAQQEGMDRLLNRHELYCTVCEHNTGDCTLHNTVADMH
IPIQYYPHQPKPYAKDHSNPFYTYDPDQCILCGRCVEACQNVEVNETLSIDYTQAHPRVL
WDGGTEIAGSSCVSCGHCVTVCPCNALLEKTMQPDAGPFTAMDEGLKRPLIDFVKTMENS
IGMGPITGVSSIDVALRQSEIKRTKTVCTYCGVGCSFEIWTRDRHILKIQPVADAPANGI
STCVKGKFGWDFVNSPARLTTPLIRENGRFRPASWDEALQRVAEGLQGIAQNYGGDAIGF
IGSSKASNEEAYLTQKIARLIFGTNNVDNSSRYCQNPATEGLFRTVGYGGDAGTIKDLQE
SELIVLVGSNLAENHPVIASHIKQSHKHRGQKLLVVDPRRHEMAERADCYLRIRPGTDLV
WASAMAKYMFDHGYADDAFLAQRVNQVEEYRTSLDTFTLDYASEICGLSEAELKESAEMI
GHAGSACILWAMGITQHSHGADTSTALSNLLLVTGNYGRPGTGGYPMRGHNNVQGASDFG
CLSNRYPGYEKVTDASIREKWARAWGVSPDALSDKAGADNFKMVQQAGEGKIRAMYITGE
ETAFADADATSVHAAFSKLEFMVVQDIFMSRTAEFADVVLPGAPSVEKEGTFVNTERRIQ
HFTPAMKPLGDCRPDWQIFTDLAARLGHPWHYPNPGAIMAEVAGIAEIFAGVSYEQLAGW
QSQLWPVNAEGESTPRLYTERFNFPDGKARLYPLSWQPPAEQEDAEYNLLLNNGRMLEHF
QSMNQTGRGGRMMSLSPNAFVEISPELAASRALIEGEWVRITSRRGSLDVPVVITDRVAG
NVLFMPIHHGTDGVNALTGEHHDPDVNTPAYKEIAVNMTRVDRRPQPNPVPLHNFRHGSR
TPLDHLPIEQKWQQAGYREPPEHVEKPEKF