Protein Info for IAI47_20190 in Pantoea sp. MT58

Annotation: urea carboxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1201 PF00289: Biotin_carb_N" amino acids 1 to 109 (109 residues), 140.6 bits, see alignment E=1.3e-44 TIGR02712: urea carboxylase" amino acids 2 to 1196 (1195 residues), 1824 bits, see alignment E=0 PF02786: CPSase_L_D2" amino acids 116 to 319 (204 residues), 202.4 bits, see alignment E=2.9e-63 PF07478: Dala_Dala_lig_C" amino acids 143 to 291 (149 residues), 37.8 bits, see alignment E=6.8e-13 PF02785: Biotin_carb_C" amino acids 338 to 447 (110 residues), 104 bits, see alignment E=2.2e-33 TIGR00724: biotin-dependent carboxylase uncharacterized domain" amino acids 454 to 772 (319 residues), 286.8 bits, see alignment E=1.9e-89 PF02626: CT_A_B" amino acids 478 to 750 (273 residues), 307.3 bits, see alignment E=4.8e-95 PF02682: CT_C_D" amino acids 801 to 1018 (218 residues), 134.4 bits, see alignment E=1.9e-42 PF00364: Biotin_lipoyl" amino acids 1136 to 1196 (61 residues), 47.2 bits, see alignment 7.1e-16

Best Hits

Predicted SEED Role

"Urea carboxylase (EC 6.3.4.6)" in subsystem Urea decomposition (EC 6.3.4.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.3.4.6

Use Curated BLAST to search for 6.3.4.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1201 amino acids)

>IAI47_20190 urea carboxylase (Pantoea sp. MT58)
MFDTLLIANRGAIACRILRTLRAMQVKGVAVYSEADLSSLHIREADVALSLGEGPAAQTY
LMTDKIIAAAQQSGAKAIHPGYGFLSENAAFAEACEAAGLIFVGPGPQQLRTFGLKHTAR
ALAKAEGVPLLEGSELLADLSEAHHAAESVGYPVMLKSTAGGGGIGMRVCRDAQALSDAF
ETVQRLGQNNFSDAGVFLEKYIERARHLEVQIFGDGKGEVIALGVRDCSIQRRNQKVIEE
TPAPNLPAGMAEALCSAAIALGKAVNYRSAGTVEFVYDSAAQQFYFLEVNTRLQVEHGVT
EQVWGVDLVKWMIELAAGDLPSLTALAATLNPQGHAVQARIYAEDPGRQFQPSPGLLTEV
AFPAADGKTLRIDRWVEAGCEVPPFFDPMLAKAIAWRPTRDEAIATLAQALAETRLYGVE
TNRLYLLQILAFSPFTAGEPWTRCLEQLSYQAATVEVLSAGTQTSVQDYPGRLGYWAVGV
PPSGPMDARALRLGNRLLGNAEGDAALEITLNGPSLKFNTEIQAVICGASLSVTLDGVEQ
AMDSVFTIPAGSTLKLGAMRAAGVRSYLCLRGGIQVPDYLGSKSTFTLGQFGGHAGRALR
SGDVLHLAPQAAIPDGAELPAALRTNLAKVRTLRVIYGPHGAPEFFAPDYIATFFATEWE
VHFNSSRTGVRLIGPKPIWTRDSGGEAGLHPSNIHDNPYAIGAVDFTGDMPVILGPDGPS
LGGFVCPVTVIEADLWQLGQLKAGDKVQFVAVDIPTARRLAQSRRSELATLKPHETAWQP
APLTSPIVMTCGEADKRLVARLSGDTHLLLEAGEPELDLVLRFRIHALMQALEAQSRTGI
IDITPGIRSLQIHFQPETLTLDVLLTWVRGEWETVCMSDDLQVPTRVVHLPLSWDDPACQ
KAIEKYMTTVRPDAPWCPSNLEFIRRINDLPDEQAVWNTVFDASYLVMGLGDVYLGAPVA
TPLDPRHRLVTTKYNPARTWTAENSVGIGGAYLCVYGMEGPGGYQFVGRTLQMWNRYHEV
ADFGGKPWLLRFFDQIRFYPVSAEELLQIRRDFPLGRYPLRIEHSTLRLAEYQDFLMREA
ESIGEFRDHQQNAFNAERDRWIASGQAHFDSQETVADEGGDAPLQPGEQGVESPVSGNLW
QVQATAGSRVREGDVLVVLESMKMEIPLLAPCDGIVQQVSVQPGSAVRAGQRVAVITEDN
A