Protein Info for IAI47_18515 in Pantoea sp. MT58

Annotation: ECA polysaccharide chain length modulation protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 349 transmembrane" amino acids 25 to 45 (21 residues), see Phobius details amino acids 318 to 338 (21 residues), see Phobius details PF02706: Wzz" amino acids 8 to 114 (107 residues), 46.7 bits, see alignment E=1.6e-16

Best Hits

Swiss-Prot: 65% identical to WZZE_ECOLI: ECA polysaccharide chain length modulation protein (wzzE) from Escherichia coli (strain K12)

KEGG orthology group: K05790, lipopolysaccharide biosynthesis protein WzzE (inferred from 94% identity to pva:Pvag_3384)

MetaCyc: 65% identical to enterobacterial common antigen polysaccharide co-polymerase (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"regulator of length of O-antigen component of lipopolysaccharide chains" in subsystem KDO2-Lipid A biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (349 amino acids)

>IAI47_18515 ECA polysaccharide chain length modulation protein (Pantoea sp. MT58)
MPSDVVDNELDIRGLSGRLWRGKRWIIGLALLFALVAWLVTLLLKQVWSTTAITDRPTVN
MLGSYYSQQQFLTNLDARSNTLTLSAPSPTVMDQVYQEFIMQLASWDTRREFWQQTDYFK
SRKTGNAHNDAALLDDMIGNILFTPADAAHNLPDNVKLKAETAGDANNLLRQYIAYASER
AARHLNDELKGAWRVRTDQLQAQVKRQEDVANAVFQRQQHRLEQALKIASQQGINEKQTR
EVGENLADSDLFLLGQPVLQGQLDTLRATGPSFDISYDQNRAMLTTLQAGPKLNSKFQTY
RYLRTPEEPVSRDSPRRLFMMIMWGAVGALTGAGVALARRPRLMSDTHE