Protein Info for IAI47_17610 in Pantoea sp. MT58

Annotation: two-component sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 451 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 154 to 176 (23 residues), see Phobius details PF00512: HisKA" amino acids 231 to 294 (64 residues), 43.2 bits, see alignment E=3.4e-15 PF02518: HATPase_c" amino acids 343 to 450 (108 residues), 67.8 bits, see alignment E=1.1e-22

Best Hits

KEGG orthology group: K07645, two-component system, OmpR family, sensor histidine kinase QseC [EC: 2.7.13.3] (inferred from 98% identity to pva:Pvag_3569)

Predicted SEED Role

"Sensory histidine kinase QseC" in subsystem Orphan regulatory proteins

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (451 amino acids)

>IAI47_17610 two-component sensor histidine kinase (Pantoea sp. MT58)
MKPFRFMRSLRNKLLSTLLIIHLLMIGGVTWYFFSCYGDMVGTMKDDQLAKIADAWSTNK
QMPALMPMLIAPDKAKSAFVVQLWDDQGQLRASSWPELQAPLQNQRGYRDVHIGQCDDCE
WRIYTRPGLPGSEIKTIQVMHNLSYMKALMVKRALSAIIPMILMMPLSLLVIWLVVRKIT
RDLQVASRQIAAQETHHPHNVSPEGLPDEILPLVAAYNSLLSKLREAWSSQRQFLEDAAH
ELRTPVTAVTLQLENLRQHIQPGEASRQFSQLEAGVTRTRHLVTQLLNVSRQDDQSVVAS
VEHIELEDLLKESIEQLMVVADKRGIDIGFNGSTQYRLQASRSELRSLFDNLIGNAMLHT
PEGSLVDVLLHRVAGKTVVDIVDNGPGMPESFIERAFDRFTRSPDVKAQGSGLGLSIVRN
VAQKHQIHVALSNCLSPQGAICGLQVRVTLP