Protein Info for IAI47_17295 in Pantoea sp. MT58

Annotation: EF-P beta-lysylation protein EpmB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 TIGR00238: KamA family protein" amino acids 3 to 328 (326 residues), 455.5 bits, see alignment E=9.5e-141 TIGR03821: EF-P beta-lysylation protein EpmB" amino acids 15 to 335 (321 residues), 527.2 bits, see alignment E=1.3e-162 PF13353: Fer4_12" amino acids 111 to 183 (73 residues), 25.9 bits, see alignment E=1.1e-09 PF04055: Radical_SAM" amino acids 118 to 262 (145 residues), 40.2 bits, see alignment E=4.3e-14

Best Hits

Swiss-Prot: 75% identical to EPMB_ECOLI: L-lysine 2,3-aminomutase (epmB) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 96% identity to pva:Pvag_3613)

MetaCyc: 75% identical to lysine 2,3-aminomutase (Escherichia coli K-12 substr. MG1655)
5.4.3.-

Predicted SEED Role

"Lysine 2,3-aminomutase (EC 5.4.3.2)" in subsystem Lysine degradation (EC 5.4.3.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.3.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (342 amino acids)

>IAI47_17295 EF-P beta-lysylation protein EpmB (Pantoea sp. MT58)
MAHIVTLKTPSREDWLQQLADVVTEPDELLRILALDQHTELAEGADARRLFALRVPHAFI
RRMKKGDAHDPLLLQVLTRRQEFIDAPGYSTDPLDEQSNVVPGLLHKYRNRALLLVKGGC
AVNCRYCFRRHFPYQDNPGNKRSWQAALDYIAEHPELDEIIFSGGDPLMAKDHELAWLIA
ALEQIPHLKRLRIHSRLPVVIPARITEQLCQMLSDTRLQVIMVTHINHAQEIDEALRESM
IRLKRAGVTLLNQSVLLRGINDNAQTLATLSNALFDAGILPYYLHVLDKVQGAAHFFVSD
DEARQLVRSLLSQVSGYLVPKLAREIGGEPSKTPLDLQLRQE