Protein Info for IAI47_17160 in Pantoea sp. MT58

Annotation: arabinose-5-phosphate isomerase KdsD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 327 PF01380: SIS" amino acids 45 to 175 (131 residues), 121.6 bits, see alignment E=2e-39 TIGR00393: sugar isomerase, KpsF/GutQ family" amino acids 49 to 317 (269 residues), 406.3 bits, see alignment E=3.3e-126 PF00571: CBS" amino acids 205 to 260 (56 residues), 26.6 bits, see alignment E=6.4e-10 amino acids 272 to 324 (53 residues), 37.5 bits, see alignment 2.5e-13

Best Hits

Swiss-Prot: 79% identical to KDSD_SALTY: Arabinose 5-phosphate isomerase KdsD (kdsD) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K06041, arabinose-5-phosphate isomerase [EC: 5.3.1.13] (inferred from 98% identity to pva:Pvag_3639)

MetaCyc: 79% identical to D-arabinose 5-phosphate isomerase KdsD (Escherichia coli K-12 substr. MG1655)
Arabinose-5-phosphate isomerase. [EC: 5.3.1.13]

Predicted SEED Role

"Arabinose 5-phosphate isomerase (EC 5.3.1.13)" in subsystem KDO2-Lipid A biosynthesis (EC 5.3.1.13)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.3.1.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (327 amino acids)

>IAI47_17160 arabinose-5-phosphate isomerase KdsD (Pantoea sp. MT58)
MSYQQPTAFDFQQAGKTVLRIEREGLEQLDQYINDDFARACALIYACQGKVVVMGMGKSG
HIGKKMAATFASTGTPAFFVHPAEASHGDLGMVSKNDVVIAISNSGESSEILALIPVLKR
QHISLICITGRPDSAMGRVADVHLCVHVPQEACPLGLAPTSSTTATLVMGDALAVSLLEA
RGFTAEDFALSHPGGALGRKLLLHVADIMHSGDELPHVTRDASLRDALLEITRKNLGLTV
IVDGLMKIEGIFTDGDLRRIFDMGIDFQRATIGEVMTPGGIRVRPNMLAVEALNLMQTKN
ITSILVADDDRLLGVVHMHDMLRAGVV