Protein Info for IAI47_16545 in Pantoea sp. MT58

Annotation: restriction endonuclease subunit S

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 PF01420: Methylase_S" amino acids 7 to 177 (171 residues), 44 bits, see alignment E=1.4e-15 amino acids 247 to 391 (145 residues), 40.5 bits, see alignment E=1.7e-14

Best Hits

Predicted SEED Role

"Type I restriction-modification system, specificity subunit S (EC 3.1.21.3)" in subsystem Restriction-Modification System (EC 3.1.21.3)

Isozymes

Compare fitness of predicted isozymes for: 3.1.21.3

Use Curated BLAST to search for 3.1.21.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (450 amino acids)

>IAI47_16545 restriction endonuclease subunit S (Pantoea sp. MT58)
MSAGKLPEGWVLSKFTDLMDVQGGTQPPKSEFIAEEKEGYIRLLQIRDFGKKPVPTYIPE
TKKLKTCRKEDLLIGRYGASLGRICTGHEGAYNVALAKVIYPQELERSYIRYYLESEIFQ
FPLKLLSRSAQNGFNKEDLSRFDFLLAPRDEQKIIAEKLDTLLVQVDSTKARLEQIPQIL
KRFRQAVLAAAVSGKLTEDYRENQVITSWDNTTLGTLIIDSCNGLAKRSGTDGEDITILR
LADFKNAQRIHGNERKITLDSKEINKYSLKKSDILVIRVNGSADLAGRFIEYKQTYEIEG
FCDHFIRLRLNSEKISSRFLTFIANEGEGRFYLRNSLSTSAGQNTINQTSIKGLALSLPT
LPEQHEIVRRVEQLFAYADTIEKQVNNALTRVNNLTQSILVKAFRGELTAQWRAENSELI
SGEKSAAALLEKIKSERAASTGKKASRKKF