Protein Info for IAI47_16405 in Pantoea sp. MT58

Annotation: siderophore-iron reductase FhuF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 264 transmembrane" amino acids 94 to 112 (19 residues), see Phobius details TIGR03951: siderophore-iron reductase FhuF" amino acids 88 to 261 (174 residues), 203.3 bits, see alignment E=1.8e-64 PF06276: FhuF" amino acids 93 to 237 (145 residues), 85.2 bits, see alignment E=7.3e-28 PF11575: FhuF_C" amino acids 241 to 261 (21 residues), 32.2 bits, see alignment (E = 7.6e-12)

Best Hits

Swiss-Prot: 48% identical to FHUF_ECOLI: Ferric iron reductase protein FhuF (fhuF) from Escherichia coli (strain K12)

KEGG orthology group: K13255, ferric iron reductase protein FhuF (inferred from 93% identity to pva:Pvag_0025)

MetaCyc: 48% identical to ferric-siderophore reductase FhuF (Escherichia coli K-12 substr. MG1655)
1.16.99.-

Predicted SEED Role

"Ferric reductase (1.6.99.14)" in subsystem Anaerobic respiratory reductases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (264 amino acids)

>IAI47_16405 siderophore-iron reductase FhuF (Pantoea sp. MT58)
MATVSAQEQRFNAQSMIFRQNDRPLAESLHERLQQQRSYLLDSVKFSQPAPHDTQTLVAW
SQSEAFAQLIQRYSDYLYRDHPDAVREAKPVLSLWAQWYFGLLLPPMIMALLQESRALDC
SPEHIRVGFHENGHPATFWIDVQEDEEARYLNPQQRIDRLIQQHLIPVVNGITQHGDINA
RLIWNNMGYSLQWFLGELKSQIDETLVLQLEQALFFNQKLLDGSENPLYRTMIMRNGELV
RRSCCQRYRIPDVEQCGNCTLSGS