Protein Info for IAI47_16265 in Pantoea sp. MT58

Annotation: allophanate hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 598 PF01425: Amidase" amino acids 31 to 435 (405 residues), 288.9 bits, see alignment E=4.2e-90 TIGR02713: allophanate hydrolase" amino acids 39 to 593 (555 residues), 803.3 bits, see alignment E=5.8e-246

Best Hits

KEGG orthology group: K01457, allophanate hydrolase [EC: 3.5.1.54] (inferred from 94% identity to pva:Pvag_0053)

Predicted SEED Role

"Allophanate hydrolase (EC 3.5.1.54)" in subsystem Urea decomposition (EC 3.5.1.54)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.54

Use Curated BLAST to search for 3.5.1.54

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (598 amino acids)

>IAI47_16265 allophanate hydrolase (Pantoea sp. MT58)
MTSTFGLTLPAWQQRTQQAPQQIRSLLSAHLAALDTHDNAWIYLATPDQLAAQIEPLLAD
YERDPASLPLFGVPFAVKDNIDVAGWPTSAACPAFTYTASEDAVAVARLKAAGAVVIGKT
NLDQFATGLVGTRSPYGAVSNTFDADYVSGGSSSGSASVLARGLVAFSLGTDTAGSGRVP
AGFNNIVGLKPTKGWFSARGVVPACRLNDTISVFALTAEDAFSVASIMGGYDAGDAYSRI
NPRTAPASLPRHPRFAIPAHPAFFDDAAAEAAWDQALEALQAGGATLHPIDFTPFRTLAE
QLYYGPWVAERTAAVGEMLDRPAEMDPVVHEIVTSGLKYSAVDAYKAEYLRAELTRQIQE
TLAQFDALVVPTSPTIHTLEEMKQEPIYFNSQFGTYTNFTNLADLSALALPAPFRNDDLP
AGITLIAPAWHDRALAEFGLRWQQQLALPLGATGQPWPTRSTTLPVSPDHVRLAVVGAHL
TGMPLNFQLTERNAVWVEETKTAPHYRLFALLEGAIKKPGLMRDEQGAAITVELWDIPLA
RFGEFVAEIPAPLGIGSLTLADGRVVKGFICEGSALKSALEITETGGWRNWLASQGSH