Protein Info for IAI47_16240 in Pantoea sp. MT58

Annotation: MDR efflux pump AcrAB transcriptional activator RobA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 294 PF12833: HTH_18" amino acids 27 to 105 (79 residues), 73.2 bits, see alignment E=3.5e-24 PF00165: HTH_AraC" amino acids 68 to 104 (37 residues), 28.8 bits, see alignment 2e-10 PF06445: GyrI-like" amino acids 127 to 287 (161 residues), 74.2 bits, see alignment E=2.8e-24 PF14526: Cass2" amino acids 159 to 286 (128 residues), 27.3 bits, see alignment E=8.1e-10

Best Hits

Swiss-Prot: 71% identical to ROB_SHIFL: Right origin-binding protein (rob) from Shigella flexneri

KEGG orthology group: K05804, right origin-binding protein (inferred from 97% identity to pva:Pvag_0058)

Predicted SEED Role

"Right origin-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (294 amino acids)

>IAI47_16240 MDR efflux pump AcrAB transcriptional activator RobA (Pantoea sp. MT58)
MDQAGIIRDLLVWLESHLDQPLSLDNVAQKAGYSKWHLQRMFKDVTGHAIGAYIRARRLS
KAAVALRLTSRPILDIALQYRFDSQQTFTRAFKKQFAQTPAWYRRSSEWNSFGIRPPIRL
DDETQPEPAFVSLPETVLVGQTQNYTCILEQISSYRDEMRMHFWKQFLLETDTIPPVLYG
LHQVRASQDKDDEQEILYTTAVPADSAVNLHSGQKVILEGGDYVQFTFNGPRVNLQEFIL
LLYGTCMPTLGLTRREGQDIERFYTHGGKKRSEPPTEIRCEYLIPIRRQQAEAS