Protein Info for IAI47_16085 in Pantoea sp. MT58
Annotation: 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 86% identical to RSMA_ERWT9: Ribosomal RNA small subunit methyltransferase A (rsmA) from Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)
KEGG orthology group: K02528, 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC: 2.1.1.182] (inferred from 98% identity to pva:Pvag_0091)MetaCyc: 79% identical to 16S rRNA (A1518/A1519-N6-dimethyltransferase (Escherichia coli K-12 substr. MG1655)
RXN-11633 [EC: 2.1.1.182]
Predicted SEED Role
"SSU rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase (EC 2.1.1.182)" (EC 2.1.1.182)
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.1.1.182
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (273 amino acids)
>IAI47_16085 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA (Pantoea sp. MT58) MNNRVHQGHYARKRFGQNFLNDQYIIDSIVSAIHPQRDEALVEIGPGLGALTEPVGERLD KLTVIELDRDLAARLETHPFLGPKLTIFQQDAMTFDFAALAQERGQPLRVFGNLPYNIST PLMFHLFSYTGSIKDMHFMLQKEVVNRLVAGPGNKTYGRLTVMAQYYCQIIPVLEVPPHS FTPPPKVDSAVVRLVPYAEPPYPVSDVRILSRITTEAFGQRRKTLRNSLSHMVAAGALEE LSIDPTLRAENVSVAQYCQLANWLANHQGKSQE