Protein Info for IAI47_15610 in Pantoea sp. MT58

Annotation: ferrichrome porin FhuA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 735 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details PF07715: Plug" amino acids 77 to 180 (104 residues), 85.6 bits, see alignment E=3.3e-28 TIGR01783: TonB-dependent siderophore receptor" amino acids 81 to 735 (655 residues), 496.5 bits, see alignment E=7.1e-153 PF00593: TonB_dep_Rec" amino acids 253 to 704 (452 residues), 220.1 bits, see alignment E=1e-68

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 94% identity to pva:Pvag_0188)

Predicted SEED Role

"Ferric hydroxamate outer membrane receptor FhuA" in subsystem Iron acquisition in Vibrio or Siderophore Aerobactin

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (735 amino acids)

>IAI47_15610 ferrichrome porin FhuA (Pantoea sp. MT58)
MNARTTFAADTKKTFSRPLLGIMISLSLSTSLYAAQAETMVVSADGGSGAEAESAWGPAP
TVAAKRSATGTKTDTPIEKNPQSVSVVTREEMEMRNVTSVKGAFNYTPGVLTGNRGSSDV
IDALSIRGFSETNTNQYMDGLKLQGDNYSEFAIDPYFLERAELLRGPVSVLYGKSNPGGV
VSLVSKRPTQETLREVQFQMGNDNLFSTGFDFGGALDDDGVYSYRLTGQARSQDAQQAMN
KEKRYTIAPAFSWRPDDRTRVDLLTYFQNEPETGYYGWLPRQGTVVPITRADGSQYKLPT
NFDEGEQSNKISRTTKMVGYNAEHSLNDTWTLRQNLRYADLRTDYRSIYGNGFTPETQEI
TRGSAVSHEKLNQLAVDTQAQAKFATGQVDHTLLLGVDFQRTRNDIDAQFGSASNLNAVN
PQYGDNSVTPFADPYQHLNKQRQTGLYTQDQMEWNRWVLTLGGRYDYAMNSVYDRVADSV
DRQNDQAFTWRGGVNYVFDNGIAPYFSYSEAFIPNAGSTYDGQAFDPSRAKQYEAGVKYV
PKDRPVVLTAALYQLTKTKNLTADPDTKNHPNFSVQSGEIRSRGVELEAKAALNANVNLT
ASYTYTDAEYTEDTQLKGKTPVSVPKNMASLWSDYTFHETALSGVTVGAGVRYVGESQGL
YSTGTEQNQNFKVAGYTTVDAALKYDLGRFGLPGSTVGVNVNNLFNREYVASCYREYACY
WGAERKIVGTATFRF