Protein Info for IAI47_15595 in Pantoea sp. MT58
Annotation: Fe(3+)-hydroxamate ABC transporter permease FhuB
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 66% identical to FHUB_SALTY: Iron(3+)-hydroxamate import system permease protein FhuB (fhuB) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
KEGG orthology group: K02015, iron complex transport system permease protein (inferred from 96% identity to pva:Pvag_0190)MetaCyc: 65% identical to iron(III) hydroxamate ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
ABC-11-RXN [EC: 7.2.2.16]; TRANS-RXN-297 [EC: 7.2.2.16]; TRANS-RXN-298 [EC: 7.2.2.16]
Predicted SEED Role
"Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), permease component FhuB" in subsystem Iron acquisition in Vibrio or Siderophore Aerobactin (TC 3.A.1.14.3)
Isozymes
No predicted isozymesUse Curated BLAST to search for 7.2.2.16
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (659 amino acids)
>IAI47_15595 Fe(3+)-hydroxamate ABC transporter permease FhuB (Pantoea sp. MT58) MRHALFPAGLLSLLFLLSLSLTLVNLHHALPQHEWWQAFWSPTVDSLPQMVFHYSLLPRT ALALLVGAGLGLAGLLFQQILRNPLAEPTTLGVSSGAQLGITVATLWHLPGGALTQQFAA LGGALLVAALVFGVAWGKRLSPVTLILAGLVLSFYSGAVNQIFAIFNHDQLQNMFLWSTG ALNQMSWENVQQLWPRLLLAFLLALALLRPLTLMGLDDGVAKNLGLALSVARIGGLGLAI LLSAQLVNVAGIIGFIGLFAPLLAKLLGGRRLLSRMLLAPLTGALLLWLADSCVLWLSAH WRDIPTGTATALLGVPILLWLLPRLRTGSVPPALNQGDNVPAERQNLLRWTLTGLAVLAL LVWGALAFGRDALGWVGSSGEMLHSLLPWRAPRVLAALVTGLMLGVAGSLIQRLTGNPMA SPEVLGISSGAACGVVVMMFFVPGDAMAWLLPAGAMGAALTLLVIMAVASRGGFSPERML LAGMALNSAFVTLLMLLLASGDPRMGGLLSWISGSTYNISGSQAIQSALCALLLVSLAPL ASRWLTLLPLGSATARSAGMALTPARLSLLLLAAALTASATLTIGPLSFVGLMAPHMARM LGFRRALPQLLLSGLLGAGLMVLADWCGRMLAFPDQIPAGLMATFLGAPYFIWLLRRSG