Protein Info for IAI47_15540 in Pantoea sp. MT58

Annotation: bifunctional uridylyltransferase/uridylyl-removing protein GlnD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 884 TIGR01693: protein-P-II uridylyltransferase" amino acids 41 to 878 (838 residues), 997.3 bits, see alignment E=3.4e-304 PF01909: NTP_transf_2" amino acids 67 to 112 (46 residues), 24.4 bits, see alignment 6.3e-09 PF08335: GlnD_UR_UTase" amino acids 186 to 325 (140 residues), 157.4 bits, see alignment E=4.8e-50 PF01966: HD" amino acids 462 to 594 (133 residues), 51.7 bits, see alignment E=2e-17 PF01842: ACT" amino acids 703 to 754 (52 residues), 35.3 bits, see alignment 1.6e-12 amino acids 810 to 872 (63 residues), 36.8 bits, see alignment 5.5e-13

Best Hits

Swiss-Prot: 80% identical to GLND_CROS8: Bifunctional uridylyltransferase/uridylyl-removing enzyme (glnD) from Cronobacter sakazakii (strain ATCC BAA-894)

KEGG orthology group: K00990, [protein-PII] uridylyltransferase [EC: 2.7.7.59] (inferred from 86% identity to ebi:EbC_08080)

Predicted SEED Role

"[Protein-PII] uridylyltransferase (EC 2.7.7.59)" in subsystem Ammonia assimilation (EC 2.7.7.59)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.59

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (884 amino acids)

>IAI47_15540 bifunctional uridylyltransferase/uridylyl-removing protein GlnD (Pantoea sp. MT58)
MSVSLSEDVKNGLVDSPAEWGDDQLTRDILKPRLELFQQHLAAAFDAGEPVEPLIDARTL
FIDRLLRRLWRFFGFDEMPSTALVAVGGYGRAELHPLSDIDVLILSRQPLDEQAAQRTSD
LLTLMWDLKLEVGHSVRTLEECLLEGLSDLTVATNLIESRMLTGDVALFLELQKNIFSDG
FWPSSRFFAAKIDEQQERHKRYHGTSYNLEPDIKSSPGGLRDIHTLQWVARRHFGATTLD
EMVGFGFLTDAERSELNECQEFLWRIRFALHLSLPRYDNRLLFDRQLSVAQRLNYQGEGN
EPVERMMKDFYRVTRRIGELNQMLLQLFDEAILALSTSEKPRSIDDDFQLRGDLIDLRDE
TLFTREPQAILRMFYVMVRNDSIKGIYSTTLRHLRHARRHLKQPLCQIPEARRTFMSILR
HPGAVSRALVPMHRHSVLWAYTPLWGHIVGQMQFDLFHAYTVDEHTIRVLQKLESFANEA
TRPQHPLCVELWPRLPQQELLLMAALLHDIAKGRGGDHSILGAQDALEFAEMHGLNSRET
QLVAWLVRHHLLMSVTAQRRDIQDPTVIQQFAEVMQNENRLRYLVCLTVADICATNESLW
NSWKQSLLRELFFATEKQLRRGMENSPDLRERVRHHRLQALALLRMDNIDEERLHQIWNR
CRADYFLRHTPNQIAWHARHLLVHDLKKPLVLVSPQATRGGTEIFIWSPDRPHLFAAVAG
ELDRRNLSVHDAQIFTSRDGMAMDTFIVLEPDGSPLSPDRHPMIIQALEQAITQSDWVPP
RTRRPSAKLRHFSVDTEVNFLPTHTDRRSYLELVALDQPGLLARVGEVFADLGVSLHGAR
ISTIGERVEDLFILANSERQALDEEMRKALQQRLTEALNPNDKV