Protein Info for IAI47_15240 in Pantoea sp. MT58

Annotation: 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR03180: OHCU decarboxylase
  • amino acids 6 to 163 (158 residues), 189 bits, E=3e-60
• PF09349: OHCU_decarbox
  • amino acids 7 to 160 (154 residues), 149.6 bits, E=5.7e-48

Best Hits

KEGG orthology group: None (inferred from 88% identity to pva:Pvag_0260)

MetaCyc: 55% identical to OHCU decarboxylase (Klebsiella pneumoniae pneumoniae MGH 78578)
RXN-6201 [EC: 4.1.1.97]

Predicted SEED Role

"Uricase (EC 1.7.3.3)" (EC 1.7.3.3)

MetaCyc Pathways

• ureide biosynthesis (7/7 steps found)
• urate conversion to allantoin I (3/3 steps found)
• urate conversion to allantoin II (3/3 steps found)
• superpathway of purines degradation in plants (13/18 steps found)
• urate conversion to allantoin III (2/3 steps found)

KEGG Metabolic Maps

• Caffeine metabolism
• Purine metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.7.3.3

Use Curated BLAST to search for 1.7.3.3 or 4.1.1.97

Protein Sequence (164 amino acids)

>IAI47_15240 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (Pantoea sp. MT58)
MELATFNQLSADEAQSAIRHCVAIPHWQQSMVAGRPFATIEALLATADALARQWQQPELE
AALSAHPRIGERADGADKESVLSRGEQSAMQQADYALQQAMQQGNKAYEARFGRVFLIRA
KGRSGEQMLAELQRRLQNSDVTEQQEALDQLREITLLRLKETIQ