Protein Info for IAI47_14680 in Pantoea sp. MT58

Annotation: cytochrome o ubiquinol oxidase subunit II

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01433: ubiquinol oxidase, subunit II
  • amino acids 13 to 239 (227 residues), 397.4 bits, E=8.3e-124
• PF00116: COX2
  • amino acids 147 to 219 (73 residues), 30.3 bits, E=3.6e-11
• PF06481: COX_ARM
  • amino acids 239 to 283 (45 residues), 58.2 bits, 6.1e-20

Best Hits

Swiss-Prot: 76% identical to CYOA_ECOL6: Cytochrome bo(3) ubiquinol oxidase subunit 2 (cyoA) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K02297, cytochrome o ubiquinol oxidase subunit II [EC: 1.10.3.-] (inferred from 98% identity to pva:Pvag_0371)

MetaCyc: 76% identical to cytochrome bo3 subunit 2 (Escherichia coli K-12 substr. MG1655)
RXN-21817 [EC: 7.1.1.3]

Predicted SEED Role

"Cytochrome O ubiquinol oxidase subunit II (EC 1.10.3.-)" in subsystem Terminal cytochrome O ubiquinol oxidase or Terminal cytochrome oxidases (EC 1.10.3.-)

MetaCyc Pathways

• D-lactate to cytochrome bo oxidase electron transfer (1/2 steps found)
• NADH to cytochrome bo oxidase electron transfer I (1/2 steps found)
• NADH to cytochrome bo oxidase electron transfer II (1/2 steps found)
• glycerol-3-phosphate to cytochrome bo oxidase electron transfer (1/2 steps found)
• proline to cytochrome bo oxidase electron transfer (1/2 steps found)
• pyruvate to cytochrome bo oxidase electron transfer (1/2 steps found)
• succinate to cytochrome bo oxidase electron transfer (1/2 steps found)

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 7.1.1.3

Protein Sequence (308 amino acids)

>IAI47_14680 cytochrome o ubiquinol oxidase subunit II (Pantoea sp. MT58)
MRLSKYNKSLGILSLIAGTLLMSGCDSALLNPKGQIALEQRSLILTAFGLMLIVVIPAVL
MAVVFAWKYRASNTNAKYSPNWSHSNKVEAVVWTIPILIIIFLSVLTWKSTHALEPSKPL
QSDVKPVEIDVVALDWKWLFIYPEQGIATVNQIAFPANTPVNFKITSNSVMNSFFIPTLG
SQIYAMAGMQTKLHLIANEPGIFDGISANFSGRGFSGMKFKAIATKDDAEFQQWVAKVKA
APNTLTTMDDFEKVAVPSENHPVEYFSSADPKLFMQVIDKFKMSHGKMDMPQHEGMDMSH
AASAGAEE