Protein Info for IAI47_14460 in Pantoea sp. MT58

Annotation: molecular chaperone HtpG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 624 PF02518: HATPase_c" amino acids 30 to 184 (155 residues), 31.6 bits, see alignment E=3e-11 PF13589: HATPase_c_3" amino acids 31 to 157 (127 residues), 37.9 bits, see alignment E=2.6e-13 PF00183: HSP90" amino acids 220 to 623 (404 residues), 428.8 bits, see alignment E=5.7e-132

Best Hits

Swiss-Prot: 86% identical to HTPG_YERE8: Chaperone protein HtpG (htpG) from Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)

KEGG orthology group: K04079, molecular chaperone HtpG (inferred from 99% identity to pva:Pvag_0414)

MetaCyc: 85% identical to chaperone protein HtpG (Escherichia coli K-12 substr. MG1655)
Non-chaperonin molecular chaperone ATPase. [EC: 3.6.4.10, 5.6.1.7]

Predicted SEED Role

"Chaperone protein HtpG" in subsystem Protein chaperones

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.4.10 or 5.6.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (624 amino acids)

>IAI47_14460 molecular chaperone HtpG (Pantoea sp. MT58)
MTMKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSDSSLYE
GDGELRVRLSVDKDNRTLTLSDNGIGMRRDEVIENLGTIAKSGTKSFLESLGSDQAKDSQ
LIGQFGVGFYSAFIVADKVTVRTRAAGASADEGVFWESAGEGEYTLAEIEKADRGTEITL
HLREGEDEFLDAWRVRSIISKYSDHIALPVEIESKDEEGEGTHWEKINKAQALWTRNKAE
ISDDEYNEFYKHIAHDYSDPVAWSHNRVEGKQEYTSLLYIPARAPFDMWNRDQKHGLKLY
VQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSRVTQSLRAALTKRTLQML
ERLAKDDNEKYQTFWNEFGLVLKEGPAEDNANQETIAKLLRFATTQSEGSAQTISLEDYV
SRMVEGQEKIYYITADSYAAAKSSPHLELFRKKGIEVLLLSDRIDEWMMSYLTEFDGKTF
QSVSKADESLSKLADEETEEQKEAEKALEPFVERVKNLLGERVKEVRLTHRLTDTPAIVT
TDANEMTTQMAKLFAAAGQEVPEVKYLFEINPDHPLVKRVADTQDEARFGEWIELLLDQA
LLAERGTLDDPNQFIRRMNQLLTA