Protein Info for IAI47_13620 in Pantoea sp. MT58

Annotation: transporter substrate-binding domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1029 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 513 to 535 (23 residues), see Phobius details PF00497: SBP_bac_3" amino acids 55 to 262 (208 residues), 43 bits, see alignment E=1e-14 amino acids 384 to 500 (117 residues), 35.7 bits, see alignment E=1.8e-12 PF00512: HisKA" amino acids 557 to 617 (61 residues), 48.9 bits, see alignment 1.4e-16 PF02518: HATPase_c" amino acids 666 to 775 (110 residues), 108.6 bits, see alignment E=6.1e-35 PF00072: Response_reg" amino acids 796 to 904 (109 residues), 43.7 bits, see alignment E=7.1e-15 PF01627: Hpt" amino acids 941 to 1011 (71 residues), 31 bits, see alignment 6.3e-11

Best Hits

KEGG orthology group: K07679, two-component system, NarL family, sensor histidine kinase EvgS [EC: 2.7.13.3] (inferred from 92% identity to pva:Pvag_0572)

Predicted SEED Role

"Virulence sensor protein bvgS precursor (EC 2.7.3.-)" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3, 2.7.3.-

Use Curated BLAST to search for 2.7.13.3 or 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1029 amino acids)

>IAI47_13620 transporter substrate-binding domain-containing protein (Pantoea sp. MT58)
MEGAAVRVFLLMLMLLCGSALAEVRPVSSVNLPMMLPVTHAETMQGKILRVGLLEENHAP
WTMRIGNDLYGINADYLSALRQLTGAQFTLNLYSDQLHLMQALSSGQIDFALGMWVTPLP
AGTLSSDNWYSSPLRVYRNQQNQRAVMFNSQNAQLAISDSTLAQLPPALAARHSFRRYSS
DLQALYTLLNQQNDYVVADETSAGFLLSQLQQGQIYQIASHIEAGQLNLRAVARDPQLIS
WINQSLRQLPAELMNTLQARWSSNLPRYQDTQTLMLSPAERAWIADHPRVTYTAEPDNYP
WSYRDASGTARGYGVDLLKAIAQSTGLQFEPVWVSNPRQARTLIEQNQAMLQLMQPLNGD
AMQSTSLPVWRALWGIYSIQSDTLAHWRDLRGKRIGVLQDDLALRLLPADLQPLQFADHN
SLYDALAKGQIDVLVDNVLSARWRIASRDDARIHLAFAASDIAWPIALGVAPDQAVLRTL
LDRALQQIPADTQSQMRDSWSTPPQPGSVMAMGSLPMMVLAVAGAAIVLLLLLLARRYWQ
QRRERQQREQAEHANAMKSQFLATVSHELRTPMQAILGLLELEKQQHSSQNLTLLHSSAQ
SLLTLLNDLQDHARIESNSFTLAPRPLALAQWLSQQQHFYHPLMRGDGPRLIVEALTPLP
DTVLIDADRLQQVINNLMTNALKFTRHGTIRLTLAAQDQQLILTVSDSGSGIPSEEQQKL
FDPWYQAPSGKSVSVQGSGLGLFICREIVLRMGGDIRLASEPGLGTQVTVTLPLEICTPA
NHVDESALPGFPQLRVAIVDDHPTNLLVMQQQLARFAIQADIFEQGRALLQADAQQPYDL
LFIDQMMPRPDGTLLLRILRRRDRQRRRQAMRVLCSADAQLLSRSLEERERVLIKPVQLG
DLSALLAEWQQAWQDDPLASLDDNLWQLAQQNEKFLNRLSQTLHNTVTQDLAAMQAAHDR
ADWTPFAEAAHRMKGSFLLVGLEHGAQLSQQLTEQVKQHQDPSETWQLLILLANRLLKKL
ETYGTYPHS