Protein Info for IAI47_12925 in Pantoea sp. MT58

Annotation: cysteine/glutathione ABC transporter permease/ATP-binding protein CydD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 589 signal peptide" amino acids 23 to 25 (3 residues), see Phobius details amino acids 50 to 50 (1 residues), see Phobius details transmembrane" amino acids 26 to 49 (24 residues), see Phobius details amino acids 61 to 79 (19 residues), see Phobius details amino acids 140 to 160 (21 residues), see Phobius details amino acids 166 to 187 (22 residues), see Phobius details amino acids 245 to 269 (25 residues), see Phobius details amino acids 281 to 301 (21 residues), see Phobius details TIGR02857: thiol reductant ABC exporter, CydD subunit" amino acids 22 to 556 (535 residues), 579.1 bits, see alignment E=5.3e-178 PF00664: ABC_membrane" amino acids 26 to 291 (266 residues), 137.9 bits, see alignment E=5.6e-44 PF00005: ABC_tran" amino acids 370 to 514 (145 residues), 99 bits, see alignment E=3.8e-32

Best Hits

Swiss-Prot: 62% identical to CYDD_ECOLI: ATP-binding/permease protein CydD (cydD) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 94% identity to pva:Pvag_0721)

MetaCyc: 62% identical to glutathione/L-cysteine ABC exporter subunit CydD (Escherichia coli K-12 substr. MG1655)
7.4.2.-; 3.6.3.M9 [EC: 3.6.3.M9]

Predicted SEED Role

"Transport ATP-binding protein CydD" in subsystem Terminal cytochrome d ubiquinol oxidases or Terminal cytochrome oxidases

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.3.M9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (589 amino acids)

>IAI47_12925 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD (Pantoea sp. MT58)
MDKSRQQHLTRWLRQQRRFAGRWLRLNTLLGTASALLIIVQAGLLASLLQALIIDQQPRE
TLTVSILLLLLCFVLRALINYARELTGYRAGQAIRQALRQQVLDRLSDLGPAWIQGRPAG
SWATLLLEQIEEMQEYYARYLPQMTLAVVIPCCILLTIFPLNWTAGLILFATAPLIPLFM
ALAGMGAAEANRRNFLVLARLSGNFLDRLRGRETLRLFHRGEAEQQAVAAATTDFRQRTM
EVLRLAFLSSAVLEFFASLAIAVVAVYFGFSYLGELHFGDYGQGVTLFAGFLVLILAPEF
FQPLRDLGAFYHAKAQAVGGADALEAFMQATPDAAPQRGQRPFTTDHAIALSADDLCVCA
PDGQVLCGPLTFTIAAGEQIALVGQSGAGKTALMNALLGFLPYQGSLKANGVELRDIRRS
DWHQQLSWVGQNPQLPASTLRDNILMNAAWDSERFAALLEACGINEFLPRLPLGIETPPG
DGGHQLSVGQAQRVAVARALYKTSHFLLLDEPAASLDALSERHVMLALNEAADRQTTLMI
THQIDTLSRWQTLWVMEAGKLVQQGNWQQLSQQPGAFSEMLKHRQQEIR