Protein Info for IAI47_12190 in Pantoea sp. MT58

Annotation: Gfo/Idh/MocA family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 PF01408: GFO_IDH_MocA" amino acids 3 to 120 (118 residues), 102.7 bits, see alignment E=2.3e-33 PF21378: YceM-like_C" amino acids 126 to 244 (119 residues), 163.3 bits, see alignment E=2.8e-52

Best Hits

Swiss-Prot: 65% identical to YCEM_SALTY: Putative oxidoreductase YceM (yceM) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K03810, virulence factor (inferred from 93% identity to pva:Pvag_0870)

Predicted SEED Role

"Virulence factor MviM" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (306 amino acids)

>IAI47_12190 Gfo/Idh/MocA family oxidoreductase (Pantoea sp. MT58)
MTLRIGVVGLGGIAQKAWLPVLSAATDWTLVGAFSPNQAKARPICDSYRISNFGSLNDLA
AACDAVFVHSSTATHYDVVRALLLAGKDVCVDKPLAETLEQAESLVALAEKRQRKLMVAF
NRRFAPRYQQLRAKMTDAASLRIEKHRSDSVGPQDLRFTLLDDYLHVVDTALWLGGKPFR
QVQGRIDTNEQGQMLYAEHHFSVEGLTISTSMHRRAGSQRERVSAVCDGKCIDISEMRDW
HEEQSDGLIITQPPAWQSHLAQRGFSGAAHHFIDCVQNQTKPETSGEQALMAQRVVEKLW
REATRE