Protein Info for IAI47_11785 in Pantoea sp. MT58

Annotation: FGGY-family carbohydrate kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 495 PF00370: FGGY_N" amino acids 6 to 250 (245 residues), 191.1 bits, see alignment E=2.6e-60 PF02782: FGGY_C" amino acids 262 to 445 (184 residues), 107.7 bits, see alignment E=7.1e-35

Best Hits

Swiss-Prot: 61% identical to APLK_PECAS: Apulose kinase (aplK) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K00864, glycerol kinase [EC: 2.7.1.30] (inferred from 96% identity to pva:Pvag_1006)

MetaCyc: 61% identical to apulose kinase (Pectobacterium atrosepticum SCRI1043)
RXN-20928 [EC: 2.7.1.233]

Predicted SEED Role

"Unknown pentose kinase TM0952"

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.30

Use Curated BLAST to search for 2.7.1.233 or 2.7.1.30

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (495 amino acids)

>IAI47_11785 FGGY-family carbohydrate kinase (Pantoea sp. MT58)
MVGPLILAIDEGTTNAKAIAVDRDGRVVARGSQSLTLQHPQPGLAEQDPEAIWQAVKQAI
AHCLASCAGAPVAAVAISNQRESVMIWQRRDGQPLTPLVSWQDRRSESFCRDLRQAGKAP
RITGLTGLAVDPMFPAAKLTGMLATIPDGAARAAAGELCIGTVDSWLTWQLSAGEVFITD
HANASRTQLYSLHLNDWDDELLALFQLPRAALPRITSSASEQGVVAVDDIPGLAPGTPIL
ARIGDSHAALQAQRRGESEVVKATYGTGSSLMMSMATPLLTENGLSTTLAWHDGTLRYAF
EGNITHTGSGAAWLGKLLGVQDPRELTAMAQRCDDNQGIYFVPALSGLGAPWWDLQARGM
VCGLTDAATPDVLARVALESIVWQMADVFFAMEQASGQQLPALCVDGSATENSWLMQLQA
DVLQRPLQRVPTAEVSALGAALLAGKVLGWWQQGSDMQALQGGSVILPREENAQRMQENY
KGWIDAVARCRYQPH