Protein Info for IAI47_11200 in Pantoea sp. MT58

Annotation: DotU family type IV/VI secretion system protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 transmembrane" amino acids 198 to 218 (21 residues), see Phobius details TIGR03349: type IV/VI secretion system protein, DotU family" amino acids 17 to 226 (210 residues), 210.8 bits, see alignment E=9.8e-67 PF09850: DotU" amino acids 19 to 220 (202 residues), 220.1 bits, see alignment E=1.2e-69

Best Hits

KEGG orthology group: K11892, type VI secretion system protein ImpK (inferred from 98% identity to pva:Pvag_1089)

Predicted SEED Role

"Outer membrane protein ImpK/VasF, OmpA/MotB domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (405 amino acids)

>IAI47_11200 DotU family type IV/VI secretion system protein (Pantoea sp. MT58)
MTVESPAREAPPSGNENLLLQAAAPLLNAVVQIRQAATHDDPAGLRQSLIDEIRQFEQRC
KQAGLPFEMIIGARYCICTALDEAAAQTPWGTRGVWSGNGMLVTFHNESWGGEKFFQLLS
RISQSPQQHLWLLEVVQYCLLLGYEGRYRGSENGRNQCDGIRNRLKSLIDETRAQRQTPQ
PPLVEVHPLVSTLARPMVPLWACAMLVALIGCLIYSGLNWRLGNAAEPLLRAIYQTPLPQ
ITAGRRPSSPQALLDLRQRLNDVIAAGQLEVSDGAFGSKVIIPADKLFAEQGTVINPVGR
ALLARVSNAMKDVKGTILVSVFTDDHPVDNSRFASSYEFSFARARTITQLLQVQLNDGHT
VRSEGRGDSDPLLPNDSSENRTRNRRVEITLFAAPETLSNHQGAQ