Protein Info for IAI47_11050 in Pantoea sp. MT58

Annotation: multidrug effflux MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 395 transmembrane" amino acids 9 to 31 (23 residues), see Phobius details amino acids 45 to 66 (22 residues), see Phobius details amino acids 78 to 96 (19 residues), see Phobius details amino acids 102 to 123 (22 residues), see Phobius details amino acids 135 to 158 (24 residues), see Phobius details amino acids 165 to 184 (20 residues), see Phobius details amino acids 216 to 238 (23 residues), see Phobius details amino acids 247 to 267 (21 residues), see Phobius details amino acids 284 to 302 (19 residues), see Phobius details amino acids 308 to 331 (24 residues), see Phobius details amino acids 341 to 362 (22 residues), see Phobius details amino acids 368 to 389 (22 residues), see Phobius details TIGR00710: drug resistance transporter, Bcr/CflA subfamily" amino acids 9 to 388 (380 residues), 299.8 bits, see alignment E=2e-93 PF07690: MFS_1" amino acids 17 to 359 (343 residues), 160.2 bits, see alignment E=6.9e-51 PF00083: Sugar_tr" amino acids 44 to 178 (135 residues), 25.9 bits, see alignment E=4.8e-10

Best Hits

KEGG orthology group: K07552, MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein (inferred from 95% identity to pva:Pvag_1123)

Predicted SEED Role

"Bicyclomycin resistance protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (395 amino acids)

>IAI47_11050 multidrug effflux MFS transporter (Pantoea sp. MT58)
MTPAHSDRLVYAITLGLLAALGPLCIDLYLPALPQMAQDLHTETATAQLSLTAGLLGLGF
GQLLFGPMSDKFGRLRPLTLSLILLFIASIGCALAQDIHQLLVARLFEGLAGAGGAVLSR
AIARDMYSGHELTRFFALLMLVNGLAPVGAPVLGGVLMTIVDWRGIFMVLGGIAILLILL
ARWKLHETLPEARRNQGSIFSAYAALGQVVTHRPFMGFCLTQGFMMSGMFAYIGASPFVL
QQLYGLSPQAFSFCFAANGFGLIIASQTSARLCPLWGEYRVLKGGLTLAFVASSLLLLAA
LLHAPLALLLLALFFTIASNGVIATTASSLAMQSQGHRAGSASAVIGVTMFTLGAITVPL
TGIGGTSVLSMCATIFGCFMMAILMFNVLAKKPLS