Protein Info for IAI47_10645 in Pantoea sp. MT58

Annotation: mechanosensitive ion channel

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 418 transmembrane" amino acids 18 to 42 (25 residues), see Phobius details amino acids 69 to 88 (20 residues), see Phobius details amino acids 94 to 116 (23 residues), see Phobius details amino acids 137 to 157 (21 residues), see Phobius details amino acids 163 to 185 (23 residues), see Phobius details PF00924: MS_channel_2nd" amino acids 184 to 250 (67 residues), 51.7 bits, see alignment E=4e-18

Best Hits

KEGG orthology group: None (inferred from 95% identity to pva:Pvag_1201)

Predicted SEED Role

"Small-conductance mechanosensitive channel"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (418 amino acids)

>IAI47_10645 mechanosensitive ion channel (Pantoea sp. MT58)
MHYIQSLMSFIEGNRVLSISFSLLLLIVAGLVTHLICKFFIVKVIRKVFFSSHKKGVPLD
KDIRLSQKLSNFVPVIVVYNFLQFMPGLPENLKVAIQTICGILFFVYLSIFFNEVLEIVN
NSYTRKSKRKNHSIKGYIQIGKILVHIIAAIMILAIMSNKSPAIIISSLGAVAAVLMLIF
QHTLLSLVANIQLSSNDVLQLGDWIEMPDRNISGEVIDIALHTITIRNWDNTISRIPTKN
FLTETYTNWQAMFSSGARRIMRSFHLDQKSITFVNQEMLQSMSQIRLAGETITELLDGRD
INAVGERWFMENGITNLMVFRKYLSAWLAQRDDIMKEMYIVVRPLKPSPDGLPVEIYCFT
SSIFWADYENTQAAIFEYIYAIARVFELQIYQHPAGSDFARLAQPRPESRDAQQSGIQ