Protein Info for IAI47_10355 in Pantoea sp. MT58

Annotation: PTS maltose transporter subunit IICB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 529 transmembrane" amino acids 21 to 41 (21 residues), see Phobius details amino acids 61 to 84 (24 residues), see Phobius details amino acids 95 to 117 (23 residues), see Phobius details amino acids 137 to 160 (24 residues), see Phobius details amino acids 181 to 204 (24 residues), see Phobius details amino acids 294 to 311 (18 residues), see Phobius details amino acids 323 to 346 (24 residues), see Phobius details amino acids 350 to 373 (24 residues), see Phobius details amino acids 380 to 398 (19 residues), see Phobius details amino acids 403 to 422 (20 residues), see Phobius details TIGR02004: PTS system, maltose and glucose-specific IIBC component" amino acids 7 to 525 (519 residues), 819.2 bits, see alignment E=1.3e-250 PF02378: PTS_EIIC" amino acids 18 to 360 (343 residues), 272.6 bits, see alignment E=4.1e-85 TIGR00826: PTS system, glucose-like IIB component" amino acids 420 to 511 (92 residues), 85 bits, see alignment E=3.6e-28 PF00367: PTS_EIIB" amino acids 454 to 486 (33 residues), 53.4 bits, see alignment (E = 1.3e-18)

Best Hits

Swiss-Prot: 79% identical to PTOCB_ECOLI: PTS system maltose-specific EIICB component (malX) from Escherichia coli (strain K12)

KEGG orthology group: K02790, PTS system, maltose and glucose-specific IIB component [EC: 2.7.1.69] K02791, PTS system, maltose and glucose-specific IIC component (inferred from 89% identity to pao:Pat9b_1757)

MetaCyc: 79% identical to PTS enzyme IIBC component MalX (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-574; TRANS-RXN0-575

Predicted SEED Role

"PTS system, maltose and glucose-specific IIC component (EC 2.7.1.69) / PTS system, maltose and glucose-specific IIB component (EC 2.7.1.69)" in subsystem Maltose and Maltodextrin Utilization (EC 2.7.1.69)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (529 amino acids)

>IAI47_10355 PTS maltose transporter subunit IICB (Pantoea sp. MT58)
MSPSHQKMSVWEFFQSLGKTFMLPVALLSFCGIMLGIGSSLSSHDVLTLLPVLDHSWLQY
LFLWMAKLGSFAFSYLPLMFAIAIPLGMARENKGVAAFAGFVGYAVLNLSINFWLNINGI
LPTTDAALLKANNVQPIMGIPSIDTGILGAVIVGIVVFWLHERFHNIRLPDALAFFGGTR
FVPIITTLVIGLMGLVVPLIWPFFARGITGLGWMINSAGDFGPMIFGTGERLLLPFGLQH
ILVAIMRFTDAGGTLDVCGRSVSGALTIFQAQLACPETHGFAESATRFLSQGKMPAFLGG
LPGAALAIYHCARPENRHKIKGLLISGVVACVVGGTTEPIEFLFLFVAPFLYLIHALLTG
VGFTIMAILGVTIGNTDGNIIDFVVFGVLHGLSTKWYWVPVVAAIWFAGYYLIFRFAILH
FNIKTPGREVENTSAVAQQVSNAGKGKSGYNSPAILAALGGVENITSLDNCLTRLRLTMA
DMSKVDDAALKANGAIGVVHLNQTSLQVVIGPQVQSVKDELSHLMNVTA