Protein Info for IAI47_10015 in Pantoea sp. MT58

Annotation: TIM barrel protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01261: AP_endonuc_2
  • amino acids 54 to 281 (228 residues), 62.2 bits, E=3.2e-21

Best Hits

KEGG orthology group: K01805, xylose isomerase [EC: 5.3.1.5] (inferred from 92% identity to pam:PANA_1872)

Predicted SEED Role

"Unknown pentose isomerase ECA1953"

MetaCyc Pathways

• superpathway of glucose and xylose degradation (16/17 steps found)
• D-xylose degradation I (2/2 steps found)
• superpathway of pentose and pentitol degradation (12/42 steps found)

KEGG Metabolic Maps

• Fructose and mannose metabolism
• Pentose and glucuronate interconversions

Isozymes

Compare fitness of predicted isozymes for: 5.3.1.5

Use Curated BLAST to search for 5.3.1.5

Protein Sequence (326 amino acids)

>IAI47_10015 TIM barrel protein (Pantoea sp. MT58)
MSELKFATRLNSFASGAHLYWPDLQGKPSVLQMVARAGKVNGLTHLDLNFPQHLTTDIAT
LRQAIEDAGLAVNGMQMRWDAPQFKIGAFTHPDAKVRREAIELTKRGIDAGREFGSRLMT
LWMGQDGFDYCFQADYKKIWEDAVSAVREVAEYAPDVDVSIEYKPNEPRAYSIFPNATTC
LLAVEEAGCANLGITLDFAHVLFANEIPAYAAAMVARRSRLLGLDLNDGWGKRDDGLMVA
SVNPRATLEFLWQMQRDGYSGAYYFDTFPDASGLDPIREAESNIATVKRLLRLCDQLHGN
AALLAAISRQDAVASQQIVNDIMLAR