Protein Info for IAI47_09765 in Pantoea sp. MT58

Annotation: osmoprotectant ABC transporter ATP-binding protein OsmV

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 378 TIGR01186: glycine betaine/L-proline transport ATP binding subunit" amino acids 18 to 367 (350 residues), 347.8 bits, see alignment E=3.6e-108 PF00005: ABC_tran" amino acids 22 to 168 (147 residues), 130.3 bits, see alignment E=8e-42 PF00571: CBS" amino acids 262 to 306 (45 residues), 32.5 bits, see alignment 9e-12 amino acids 326 to 368 (43 residues), 18.7 bits, see alignment 1.8e-07

Best Hits

Swiss-Prot: 83% identical to OSMV_SALTY: Osmoprotectant import ATP-binding protein OsmV (osmV) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K05847, osmoprotectant transport system ATP-binding protein (inferred from 98% identity to pva:Pvag_1382)

Predicted SEED Role

"L-proline glycine betaine ABC transport system permease protein ProV (TC 3.A.1.12.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (TC 3.A.1.12.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (378 amino acids)

>IAI47_09765 osmoprotectant ABC transporter ATP-binding protein OsmV (Pantoea sp. MT58)
MITLENLTKTFTQKNGTTNKAVDNVSLHVPAGEMCVLLGPSGCGKTTTLKMINRLIPATS
GRILINGEDTSTQDTTTLRRNIGYVIQQIGLFPNMTIEENITVVPRMLGWDKKQCRERAT
ELMSMVALDPTKFLHRYPREMSGGQQQRIGVIRALAADPPVLLMDEPFGAVDPINREVIQ
NEFLDMQCQLKKTVMLVSHDIDEALKLGDRIAVFGQGKIVQCASPDELLATPANDFVGSF
VGQDRTLKRLLLVQAGDVTDQQPTITVRRSTPLDEAFGTMDENDMRSITVVDEDGKPLGF
VKRREARNVSGRCEEKLHTFKVTGKAEENLRVVLSKLYEHNTVWMPIVDEEGRYSGEISQ
DYIADYLSSGRTRRRLNP