Protein Info for IAI47_09195 in Pantoea sp. MT58

Annotation: PHP domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 305 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details PF02811: PHP" amino acids 22 to 100 (79 residues), 42.9 bits, see alignment E=3.5e-15

Best Hits

Swiss-Prot: 71% identical to RNAAM_ECOLI: 5'-3' exoribonuclease (yciV) from Escherichia coli (strain K12)

KEGG orthology group: K07053, (no description) (inferred from 97% identity to pva:Pvag_1503)

MetaCyc: 71% identical to RNase AM (Escherichia coli K-12 substr. MG1655)
RXN-16009 [EC: 3.1.3.97]; 3.1.13.- [EC: 3.1.3.97]; RXN-24047 [EC: 3.1.3.97]

Predicted SEED Role

"COG0613, Predicted metal-dependent phosphoesterases (PHP family)"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.97

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (305 amino acids)

>IAI47_09195 PHP domain-containing protein (Pantoea sp. MT58)
MLAGLVLAGVLLSDIARFPVYDLHSHTRASDGFLTPAALVQRAVEMRVGVLAITDHDSVA
GVEEAQQTALDQDLPIKVLAGAEISTLWENHEIHIVGLNIDIHHPAMVTFLAGQHACRRI
RAEEIGERLARARIPDALAGAMRLADGGIITRGHFARFLIEQGKAENMVQVFKNYLARGK
TGYVPPQWCTIKQAIDAIHHSGGCAVLAHPGRYGLSAKWLKRLVAHFREAGGDAMEVAQC
QQPPNERTTLAQYARDNELAASQGSDFHQPCPWIELGRKLWLPAAVEPVWERFPDLAPSL
AITER