Protein Info for IAI47_08990 in Pantoea sp. MT58

Annotation: exodeoxyribonuclease III

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00195: exodeoxyribonuclease III
  • amino acids 1 to 266 (266 residues), 338 bits, E=4e-105
• TIGR00633: exodeoxyribonuclease III (xth)
  • amino acids 1 to 266 (266 residues), 291.9 bits, E=4.5e-91
• PF03372: Exo_endo_phos
  • amino acids 4 to 259 (256 residues), 132.7 bits, E=8.2e-43

Best Hits

Swiss-Prot: 82% identical to EX3_ECOLI: Exodeoxyribonuclease III (xthA) from Escherichia coli (strain K12)

KEGG orthology group: K01142, exodeoxyribonuclease III [EC: 3.1.11.2] (inferred from 95% identity to pva:Pvag_1543)

MetaCyc: 82% identical to exodeoxyribonuclease III (Escherichia coli K-12 substr. MG1655)
3.1.4.-; 3.1.3.-; Deoxyribonuclease IV (phage-T(4)-induced). [EC: 3.1.21.2]; Exodeoxyribonuclease III. [EC: 3.1.21.2, 3.1.11.2]

Predicted SEED Role

"Exodeoxyribonuclease III (EC 3.1.11.2)" in subsystem DNA repair, bacterial (EC 3.1.11.2)

Isozymes

Compare fitness of predicted isozymes for: 3.1.21.2

Use Curated BLAST to search for 3.1.11.2 or 3.1.21.2

Protein Sequence (268 amino acids)

>IAI47_08990 exodeoxyribonuclease III (Pantoea sp. MT58)
MKFVSFNINGLRARPHQLQALVEQHQPDVIGLQETKVHDDMFPLEEVSKLGYHVFYHGQK
GHYGVALLTKAQPVSVSRGFPDDDDESQRRLIVAEIPSPIGDITVINGYFPQGESRDHPT
KFPAKEKFYRDLQRLLTDDLPADKPVLIMGDMNISSTDLDIGIGEDNRKRWLRTGKCSFL
PEEREWMDRLLSWGLVDTWRVHNPEVADRFSWFDYRSKGFDDNRGLRIDLVLVSKNLASH
CVETGIDYAIRSMEKPSDHAPIWSTFRF