Protein Info for IAI47_08950 in Pantoea sp. MT58

Annotation: peptide-methionine (R)-S-oxide reductase MsrB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00357: methionine-R-sulfoxide reductase
  • amino acids 8 to 131 (124 residues), 199.8 bits, E=7.8e-64
• PF01641: SelR
  • amino acids 12 to 127 (116 residues), 179.3 bits, E=1.2e-57

Best Hits

Swiss-Prot: 78% identical to MSRB_ERWT9: Peptide methionine sulfoxide reductase MsrB (msrB) from Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)

KEGG orthology group: K07305, peptide-methionine (R)-S-oxide reductase [EC: 1.8.4.12] (inferred from 96% identity to pva:Pvag_1551)

MetaCyc: 72% identical to methionine sulfoxide reductase B (Escherichia coli K-12 substr. MG1655)
L-methionine (R)-S-oxide reductase. [EC: 1.8.4.14]; Peptide-methionine (R)-S-oxide reductase. [EC: 1.8.4.14, 1.8.4.12]

Predicted SEED Role

"Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12)" (EC 1.8.4.12)

KEGG Metabolic Maps

• Methionine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.8.4.12 or 1.8.4.14

Protein Sequence (136 amino acids)

>IAI47_08950 peptide-methionine (R)-S-oxide reductase MsrB (Pantoea sp. MT58)
MAKDTATDAKIAELTEMQRYVTQQRGTEPPYSGALLHNKQEGIYHCLVCEAPLFLSETKY
DSGCGWPSFYQPVSDDAIRYIEDNSHGMQRVEIRCGSCDAHLGHVFPDGPQPTGERYCVN
SASLNFTDEQGEQTKG