Protein Info for IAI47_08790 in Pantoea sp. MT58

Annotation: CoA pyrophosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 187 PF00293: NUDIX" amino acids 27 to 140 (114 residues), 56.1 bits, see alignment E=2e-19

Best Hits

Swiss-Prot: 66% identical to NUDL_CROS8: Uncharacterized Nudix hydrolase NudL (nudL) from Cronobacter sakazakii (strain ATCC BAA-894)

KEGG orthology group: None (inferred from 95% identity to pva:Pvag_1586)

MetaCyc: 63% identical to putative NUDIX hydrolase with low 3-phosphohydroxypyruvate phosphatase activity (Escherichia coli K-12 substr. MG1655)
RXN0-6562

Predicted SEED Role

"Hypothetical nudix hydrolase YeaB" in subsystem Nudix proteins (nucleoside triphosphate hydrolases)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (187 amino acids)

>IAI47_08790 CoA pyrophosphatase (Pantoea sp. MT58)
MALTIDVFRSRFLLQQPARSTQRLSGRHAAVLVPIVARPEPGLLLTQRSQALRKHAGQVA
FPGGMQDDTDASLINTALREAQEEVGIDPQQVEILGALPAVTSSTGFQVTPVLGIIPADL
RLTLNPDEVSSAFEMPLAEALQLSRYSALEVHQAGVRHPVWLSRYQDYLVWGMTAGIIRS
LSTQIAF