Protein Info for IAI47_08300 in Pantoea sp. MT58

Annotation: chemotaxis protein CheA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 660 PF01627: Hpt" amino acids 6 to 96 (91 residues), 67.9 bits, see alignment E=1.8e-22 PF09078: CheY-binding" amino acids 153 to 214 (62 residues), 56.6 bits, see alignment E=5.5e-19 PF02895: H-kinase_dim" amino acids 268 to 330 (63 residues), 72.3 bits, see alignment E=8.8e-24 PF02518: HATPase_c" amino acids 378 to 514 (137 residues), 68.8 bits, see alignment E=1.4e-22 PF01584: CheW" amino acids 520 to 646 (127 residues), 101.2 bits, see alignment E=9.6e-33

Best Hits

Swiss-Prot: 78% identical to CHEA_SALTY: Chemotaxis protein CheA (cheA) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K03407, two-component system, chemotaxis family, sensor kinase CheA [EC: 2.7.13.3] (inferred from 97% identity to pva:Pvag_1727)

Predicted SEED Role

"Signal transduction histidine kinase CheA (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3, 2.7.3.-

Use Curated BLAST to search for 2.7.13.3 or 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (660 amino acids)

>IAI47_08300 chemotaxis protein CheA (Pantoea sp. MT58)
MDISDFYQTFFDEADELLADMEQHLLGLDPQEPDSEQLNAIFRAAHSIKGGAGTFGFTVL
QETTHILENILDGARRGEMQLSTDIINLFLETKDIMQEQLDAYKTAQEPNAESFKYICEA
LRQLALEAKGLPVEAPASVATVSAEPASTSGLRVQLIDLKEKEVDLMLEEMSNLGTLTNV
QKGSNMLDVCIDGVGKDDIVAVLCFVIDEAQIRFPAADDAVAAPVAVAAPAAPVVEEVHT
ATVTELPVAAAKRETKRAAAPAKSSESTSIRVAVEKVDQLINLVGELVITQSMLAQRSGE
LDPVAHGDLLNSMGQLERNARDLQESVMSIRMMPMEYVFSRFPRLVRDLASKLGKEVELT
LLGSSTELDKSLIERIIDPLTHLVRNSLDHGIETPEKRLVAGKVATGNLTLSAEHQGGNI
CIEVSDDGAGLNRERILAKALSSGLPVHENMSDEEVGMLIFAPGFSTAEQVTDVSGRGVG
MDVVKRNIQEMGGHVEIASKQGKGTTIRILLPLTLAILDGMSVRVANEVFILPLNAVMES
LQPRAEDLKPMAGGECVLEVRGEYLPLVELWSVFDVQDAKTEATQGIVVILQSAGKRYAL
LVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQSLNREKRVAGAAA