Protein Info for IAI47_08270 in Pantoea sp. MT58

Annotation: trehalose-phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00685: trehalose-phosphatase
  • amino acids 18 to 245 (228 residues), 189.8 bits, E=7.8e-60
• TIGR01484: HAD hydrolase, family IIB
  • amino acids 21 to 214 (194 residues), 62.2 bits, E=7.4e-21
• PF02358: Trehalose_PPase
  • amino acids 22 to 232 (211 residues), 135.9 bits, E=1.2e-43

Best Hits

Swiss-Prot: 54% identical to OTSB_ECOLI: Trehalose-6-phosphate phosphatase (otsB) from Escherichia coli (strain K12)

KEGG orthology group: K01087, trehalose-phosphatase [EC: 3.1.3.12] (inferred from 92% identity to pva:Pvag_1733)

MetaCyc: 54% identical to trehalose-6-phosphate phosphatase (Escherichia coli K-12 substr. MG1655)
Trehalose-phosphatase. [EC: 3.1.3.12]

Predicted SEED Role

"Trehalose-6-phosphate phosphatase (EC 3.1.3.12)" in subsystem Trehalose Biosynthesis (EC 3.1.3.12)

MetaCyc Pathways

• trehalose biosynthesis I (2/2 steps found)
• trehalose biosynthesis II (1/2 steps found)
• trehalose biosynthesis III (1/2 steps found)
• glycogen biosynthesis III (from α-maltose 1-phosphate) (3/8 steps found)
• mycolate biosynthesis (25/205 steps found)
• superpathway of mycolate biosynthesis (26/239 steps found)

KEGG Metabolic Maps

• Starch and sucrose metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.12

Protein Sequence (262 amino acids)

>IAI47_08270 trehalose-phosphatase (Pantoea sp. MT58)
MTQAADTHARYPTLSSGQYAFFFDVDGTLAAIQSRPEAVFIPEQVIAQLQRLSALSQGAL
ALVSGRPIEQLDALAAPLHGPAAGVHGAERRDAEGNLHRISLPAEVEQPLRTELQAAMAA
WPGTQLEIKGMAFALHYRQAMQHEQDVMRLAEQSVKRFPGLALQPGKCVVEIKPAGIDKG
AAIGDFMQQSPFAGRTPVFIGDDLTDEKGFLAVNERQGVSVKVGEGFSQADYRLSDVDAV
YGWLEKTLLLLEQDNVGKEFRL