Protein Info for IAI47_07860 in Pantoea sp. MT58

Annotation: NCS2 family permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 431 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 49 to 74 (26 residues), see Phobius details amino acids 95 to 117 (23 residues), see Phobius details amino acids 129 to 154 (26 residues), see Phobius details amino acids 167 to 186 (20 residues), see Phobius details amino acids 193 to 215 (23 residues), see Phobius details amino acids 232 to 252 (21 residues), see Phobius details amino acids 282 to 304 (23 residues), see Phobius details amino acids 316 to 333 (18 residues), see Phobius details amino acids 341 to 361 (21 residues), see Phobius details amino acids 383 to 401 (19 residues), see Phobius details amino acids 411 to 429 (19 residues), see Phobius details PF00860: Xan_ur_permease" amino acids 17 to 391 (375 residues), 187.2 bits, see alignment E=2.1e-59

Best Hits

Swiss-Prot: 51% identical to ADEP_ECOLI: Adenine permease AdeP (adeP) from Escherichia coli (strain K12)

KEGG orthology group: K06901, putative MFS transporter, AGZA family, xanthine/uracil permease (inferred from 99% identity to pva:Pvag_1829)

MetaCyc: 51% identical to adenine:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-447

Predicted SEED Role

"Xanthine/uracil/thiamine/ascorbate permease family protein" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (431 amino acids)

>IAI47_07860 NCS2 family permease (Pantoea sp. MT58)
MLEKLFKLKAHNTTVRTEIIAGITTFLAMAYILFVNPSILGATAMDKGAVFVATCLAAAI
GCVLMGLIANYPIALAPGMGLNAFFTYTVVLHMGYTWQIALGAVFLSAVIFFAMSLFKIR
EWIIASIPLPLRAGIGAGIGLFLAIIALEGAGIVVDNPATLVGIGDLTKPGPLLAMLGFV
VIVVLEARRVTGAVLIGILLVTFISMGIGLSPFAGVFSAPPSIAPTFLQLDIAGAFNVGL
VSVIFAFLFVDVFDNTGTLLGVTKRAGLADEQGNVPKMGRALIADSAAALFGSLLGTSTT
TSYVESAAGVSAGGRTGLTAIVVGVLFLLALFFSPLASSVPVYATAPALLFVAVLMTSGL
ADIDWKDITTAAPVTVTALTMPLTYSIANGIAFGFITWTLVKLLSGRVKEINAALVILSI
LFVIKLGWLSA