Protein Info for IAI47_07655 in Pantoea sp. MT58

Annotation: hydantoinase/oxoprolinase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 681 transmembrane" amino acids 442 to 459 (18 residues), see Phobius details PF05378: Hydant_A_N" amino acids 4 to 182 (179 residues), 147.7 bits, see alignment E=4.5e-47 PF01968: Hydantoinase_A" amino acids 203 to 489 (287 residues), 251.2 bits, see alignment E=2e-78 PF19278: Hydant_A_C" amino acids 503 to 671 (169 residues), 50.9 bits, see alignment E=2e-17

Best Hits

KEGG orthology group: K01473, N-methylhydantoinase A [EC: 3.5.2.14] (inferred from 95% identity to pva:Pvag_1874)

Predicted SEED Role

"N-methylhydantoinase A (EC 3.5.2.14)" in subsystem Hydantoin metabolism (EC 3.5.2.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.2.14

Use Curated BLAST to search for 3.5.2.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (681 amino acids)

>IAI47_07655 hydantoinase/oxoprolinase family protein (Pantoea sp. MT58)
MRYRVGVDIGGSFTDFAVLDQQTNQIHTLKVLSRPDKPGSEIETGLTQFQQHQGIDPAEI
GYFTHGTTVGINAVIQRRGVRLALFATEGFCDVLELARLKIPHIHDLFSRRAAPLITRDR
VFAIRERIDAHGNVLHAPDRQSVLDAIEQARAAGCQGIVVSLLHSYRNRHNEAAVKAIIE
EVAPELLTSCSADIWPIIREYERTITATINAYVQPMVIHYLESFEQALKRLGVKPPPRIT
KSNGGVMGVGQAKRECVQMVLSGTASGVIGASYLASACGFDKILSLDIGGTSADVAVIID
GKVAQGNGEIIGDFPIFIPSVAVTSVGQGGGSLAWIDGQGVLQMGPDSAGSLPGPVCFQR
GGTQPTATDAFAACGMMGHGALGYNAVTVDVAAARAAWQPLADALTISVEETAETAIQLA
ISSMYSDTSGLLSRFGLDPREFWFLAFGGAGPMMGCFLARELNMKGVIVPPTPGVLSALG
GLVADIRNDFIRTLYGDLTPALADTLASEAEALQQRACNWLTQEHGSDMPYSLQFSADMR
YHGQSFEIDVPLEASWLTQADFTALHDAFDRQHQQLFGHSDPQAPVQLINLRLVIASPTP
KPVINRLATATEPVPVLKQTDAWIDGAWHQVDVVLRTVLLAGHQLRGPVIIAQNDCTTCV
PPGMGVTVDSFGNLLITANEA