Protein Info for IAI47_07530 in Pantoea sp. MT58

Annotation: type III restriction-modification system endonuclease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 969 PF04851: ResIII" amino acids 53 to 257 (205 residues), 63.7 bits, see alignment E=2e-21 PF19778: RE_endonuc" amino acids 849 to 954 (106 residues), 82.7 bits, see alignment E=1.7e-27

Best Hits

Swiss-Prot: 90% identical to T3RE_BPP1: Type III restriction-modification system EcoPI enzyme res (res) from Escherichia phage P1

KEGG orthology group: None (inferred from 58% identity to nla:NLA_10950)

Predicted SEED Role

"Type III restriction-modification system restriction subunit (EC 3.1.21.5)" (EC 3.1.21.5)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.21.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (969 amino acids)

>IAI47_07530 type III restriction-modification system endonuclease (Pantoea sp. MT58)
MSKGFTFEKNLPHQKAGVDAVMNVFVSAIPHQTDHVAIRLLANPELNLSEQQYYNNIKNV
QEFNGIEHSKDNYDAKSNVIDVSMETGTGKTYTYTKTIFDLNKSFGINKFIIIVPTLSIK
AGTVNFLKSDALKEHFRDDYERELKTYVVESQKSSGKNTKSYMPQAIHDFVEASNFNKKY
IHVLVINSGMINSKSLTDTYDVGLLDNQFDTPFAALSAVKPFIIIDEPHKFPTGKKTWEN
IEKFNAQYIVRYGATFSEGYKNLVYRLTAVDAFNEDLVKGIDAYIEDIVGDGNANLKFVK
SDGKEATFELNENSNKKTFKLAKGESLSKTHNAIHDLTLDALNKNTAVLSNGIELKIGSS
INPYSYDQTLADNMMRKAVKEHFKLEKEYLTQRPRIKPLTLFFIDDIEGYRDGNHIAGSL
KTKFEEYVLAEANELLKTEKDEFYRNYLEKTVKDISSVHGGYFSKDNSDKDDKIEQEINE
ILHDKELLLSLENPRRFIFSKWTLREGWDNPNVFQICKLRSSGSTTSKLQEVGRGLRLPV
NEYMCRVKDRNFTLNYYVDFTEKDFVDSLVKEVNDSSFKETVPSKFTQELKDKILSQYPE
LSSRTLMNDIFDDEIIDDNDNFKDSDAYSRLKAKYPAAFPTGVKPSKIKKSTDGKRRTKM
RVGKFSELKELWHLINQKAVIEYKINSEHEFLSIFKSFMLEETDRFTKSGVHTRIDRIYI
HNDTAMSKSIVGDDDNFAKLNTMSYREFLDNLSQTIFAKHDTLHKVFCDIKDTINITEYL
NIQTIRKIKSGFSKYLLNNSFNKFSLGYNVISGSIHPTKFTNADGEPVSEVLSSDLGILN
DNKKPPLNSYLFEEVFYDSELERLNITDGEIQSVAVFTKIPKNSIKIPVAGGYTYSPDFA
YVVKTTKGDYLNFIIETKNVDGKDSLRLEEERKIKHAQALFSQISQSVKVEFRTQFSADR
IAELIKKVG