Protein Info for IAI47_06470 in Pantoea sp. MT58

Annotation: two-component system sensor histidine kinase RcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 315 to 338 (24 residues), see Phobius details PF00512: HisKA" amino acids 471 to 535 (65 residues), 62.4 bits, see alignment 6.7e-21 PF02518: HATPase_c" amino acids 582 to 691 (110 residues), 103.7 bits, see alignment E=1.6e-33 PF09456: RcsC" amino acids 710 to 799 (90 residues), 99.3 bits, see alignment E=1.9e-32 PF00072: Response_reg" amino acids 828 to 935 (108 residues), 103 bits, see alignment E=2.2e-33

Best Hits

KEGG orthology group: K07677, two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC: 2.7.13.3] (inferred from 66% identity to eay:EAM_2263)

Predicted SEED Role

"Two-component sensor protein RcsC (EC 2.7.3.-)" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3, 2.7.3.-

Use Curated BLAST to search for 2.7.13.3 or 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (950 amino acids)

>IAI47_06470 two-component system sensor histidine kinase RcsC (Pantoea sp. MT58)
MKYPVSFRTTLRISRYLFRALALLIWTLGAVLTAFYIISVLHNKETQVRQEFASNYGTIQ
WYVRHSADMVRELKYITENRLTNASSGLDVLTGMMPGKTTQPQFTPLFSDGDCTSMSNTW
RNSLDSLSYYINYWKSNFASSYELNRVFFIGGESQCLADFTIGSSNADRERSLKSLRENV
LRYRNSSEEERRNPMYWINSSAQPGVGTFYMVVPVYVANKLQALLGVEQNIRLDEFIQPG
SLPIIASITDENYRPLLNSRRGGLGFSLDNLPDDKTWFGYLNGYRQLVLKKPLPPSDLNV
VWSVPTDVMVDQLKLMIINALLLNIFSAVILFTLAWVFERRMFLPAEENAHRLEEHEQFN
RKIVASAPVGICILRTSDGTNILSNELAHNYLTLLTQEDRLRLNEIIGGQQVNFVDVLTG
SNTNLQISFVHSRYRNENVAICVLVDVSARVRMEQSLQEMAHAAEQASQSKSMFLATVSH
ELRTPLYGIIGNLDLLQTKELPSGIDSLVTAMNNSSSLLLKIISDILDFSKIESEQLKIE
PRPFAPREIVTHIVGNYLSLVVKKRLTLYCFIEHDVPQVLDGDPLRLQQVISNLLNNAIK
FTHTGCIILHAYVAQGYLAFRVRDTGVGIPAKELPRLFDPFFQVGNGVQRNFQGTGLGLA
ICEKLINMMDGDIEVDSEPGMGSQFIVRIPIYQGQKPSLMLLEDLQDKKIWLAMRNEYLA
AFITRQIQQQGIQVAEYNGKPGPDDVVMTDYELETDAPLRALVTFDGSHVDMPRERQPGR
WIHSTATLHEVPALLARIYRIALGNDAADALLLATPVEEKVHNDDIMVLIVDDHPINRML
LSEQLGTLGYQVKTAQDGVDALNVLSRNEIDIVLTDVNMPNMDGYRLTQRLRQLGHLFPV
VGVTANALAEEKQRCMDAGMDNCLSKPVTLDVLKVTLAIYAERVRKTRRG