Protein Info for IAI47_06320 in Pantoea sp. MT58

Annotation: phosphate acetyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13500: AAA_26
  • amino acids 1 to 223 (223 residues), 134.7 bits, E=5.6e-43
• PF07085: DRTGG
  • amino acids 228 to 338 (111 residues), 92.7 bits, E=1.8e-30
• PF01515: PTA_PTB
  • amino acids 386 to 701 (316 residues), 431 bits, E=4.8e-133
• TIGR00651: phosphate acetyltransferase
  • amino acids 401 to 701 (301 residues), 451.7 bits, E=6.9e-140

Best Hits

Swiss-Prot: 89% identical to PTA_YERPE: Phosphate acetyltransferase (pta) from Yersinia pestis

KEGG orthology group: K13788, phosphate acetyltransferase [EC: 2.3.1.8] (inferred from 91% identity to ebi:EbC_30890)

MetaCyc: 87% identical to phosphate acetyltransferase (Escherichia coli K-12 substr. MG1655)
Phosphate acetyltransferase. [EC: 2.3.1.8]; PTAALT-RXN [EC: 2.3.1.8, 2.3.1.222]

Predicted SEED Role

"Phosphate acetyltransferase (EC 2.3.1.8)" in subsystem Ethanolamine utilization or Fermentations: Lactate or Fermentations: Mixed acid or MLST or Propanediol utilization or Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate or Threonine anaerobic catabolism gene cluster (EC 2.3.1.8)

MetaCyc Pathways

• hexitol fermentation to lactate, formate, ethanol and acetate (17/19 steps found)
• heterolactic fermentation (16/18 steps found)
• mixed acid fermentation (14/16 steps found)
• superpathway of N-acetylneuraminate degradation (18/22 steps found)
• superpathway of L-threonine metabolism (15/18 steps found)
• L-threonine degradation I (6/6 steps found)
• pyruvate fermentation to acetate II (3/3 steps found)
• pyruvate fermentation to acetate IV (3/3 steps found)
• superpathway of acetate utilization and formation (3/3 steps found)
• acetate and ATP formation from acetyl-CoA I (2/2 steps found)
• superpathway of fermentation (Chlamydomonas reinhardtii) (7/9 steps found)
• acetylene degradation (anaerobic) (4/5 steps found)
• ethanolamine utilization (4/5 steps found)
• pyruvate fermentation to acetate and (S)-lactate I (3/4 steps found)
• pyruvate fermentation to acetate I (2/3 steps found)
• pyruvate fermentation to acetate VII (2/3 steps found)
• sulfoacetaldehyde degradation I (1/2 steps found)
• (S)-propane-1,2-diol degradation (3/5 steps found)
• pyruvate fermentation to acetate and lactate II (2/4 steps found)
• purine nucleobases degradation II (anaerobic) (16/24 steps found)
• superpathway of Clostridium acetobutylicum acidogenic fermentation (5/9 steps found)
• lactate fermentation to acetate, CO₂ and hydrogen (Desulfovibrionales) (4/8 steps found)
• sulfolactate degradation II (1/4 steps found)
• acetyl-CoA fermentation to butanoate (3/7 steps found)
• methanogenesis from acetate (2/6 steps found)
• superpathway of sulfolactate degradation (2/6 steps found)
• superpathway of taurine degradation (2/6 steps found)
• superpathway of L-alanine fermentation (Stickland reaction) (4/9 steps found)
• L-lysine fermentation to acetate and butanoate (4/10 steps found)
• (S)-lactate fermentation to propanoate, acetate and hydrogen (5/13 steps found)
• gallate degradation III (anaerobic) (3/11 steps found)
• superpathway of Clostridium acetobutylicum acidogenic and solventogenic fermentation (7/17 steps found)
• superpathway of methanogenesis (2/21 steps found)
• superpathway of L-lysine degradation (12/43 steps found)

KEGG Metabolic Maps

• Propanoate metabolism
• Pyruvate metabolism
• Taurine and hypotaurine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.1.222 or 2.3.1.8

Protein Sequence (709 amino acids)

>IAI47_06320 phosphate acetyltransferase (Pantoea sp. MT58)
MLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRSGGDTPDQTTTIIRKNSSIPA
AEPLQMSRVESLLGSNQQDVLMEEIISRYHANTQDAEVVLVEGLVPTRKHQFANALNYEI
AKTLNAEIVFVMALGNDSPAQLKERIELTQSSFGGQKNKNITGVIINKLNAPVDDQGRTR
PDLSEIFDDSSKASIANIDPKQLFSDSPLPVLGCVPWSFDLIATRAIDMCRHLDARIINE
GEIQTRRVKSVTFCARSIPHMLEHFRPGSLLVTSADRPDVLVAACLAAMNGIEIGAILLT
GNYEIDDRIARLCDRAFQTGLPVFMVKTNTWQTSLSLQSFNLEVPADDTQRIEKVQEYVA
SYINAEWIESLTATSERSRRLSPPAFRYQLTELARKAGKRVVLPEGDEPRTVKAASICAE
RGIATCVLLGNPDEIQRVAAAQGVVLGKGVEIVDPEQVRENYVPRLVELRKSKGMTEVVA
QEQLEDNVVLGTMMLESGEVDGLVSGAVHTTANTIRPPLQLIKTAPNSSLVSSVFFMLLP
EQVLVYGDCAINPDPTAEQLAEIAIQSADSASAFGIDPRVAMISYSTGTSGAGSDVEKVR
EATRIAQEKRPDLVIDGPLQYDAAIMEDVAKSKAPNSQVAGRATVFIFPDLNTGNTTYKA
VQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSQQAEG