Protein Info for IAI47_06315 in Pantoea sp. MT58

Annotation: NUDIX hydrolase YfcD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 174 PF00293: NUDIX" amino acids 37 to 149 (113 residues), 68.3 bits, see alignment E=3.5e-23

Best Hits

Swiss-Prot: 83% identical to YFCD_ECOL6: Uncharacterized Nudix hydrolase YfcD (yfcD) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: None (inferred from 100% identity to pva:Pvag_2115)

Predicted SEED Role

"Putative Nudix hydrolase YfcD (EC 3.6.-.-)" in subsystem Nudix proteins (nucleoside triphosphate hydrolases) (EC 3.6.-.-)

Isozymes

Compare fitness of predicted isozymes for: 3.6.-.-

Use Curated BLAST to search for 3.6.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (174 amino acids)

>IAI47_06315 NUDIX hydrolase YfcD (Pantoea sp. MT58)
MVDQTAGDGIEWVDIVNEENEVVAQATRAQMRAQCLRHRATYIVVHDGMGKILVQRRTEI
KDFMPGKLDATAGGVVQSGEDMLESARREAEEELGIAAVPFAEHGKFYFEDQHCRVWGGL
FSCVSHGPFAMQESEVDEIIWMTPDEITARCDEFTDDSLKALSLWMSRNGDNRA