Protein Info for IAI47_06300 in Pantoea sp. MT58

Annotation: histidine ABC transporter ATP-binding protein HisP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00005: ABC_tran
  • amino acids 21 to 181 (161 residues), 126.1 bits, E=1.6e-40
• PF13304: AAA_21
  • amino acids 165 to 211 (47 residues), 27.7 bits, 2.5e-10

Best Hits

Swiss-Prot: 88% identical to HISP_ECOLI: Histidine transport ATP-binding protein HisP (hisP) from Escherichia coli (strain K12)

KEGG orthology group: K10017, histidine transport system ATP-binding protein [EC: 3.6.3.21] (inferred from 98% identity to pva:Pvag_2118)

MetaCyc: 53% identical to cystine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"Histidine ABC transporter, ATP-binding protein HisP (TC 3.A.1.3.1)" in subsystem Arginine and Ornithine Degradation (TC 3.A.1.3.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.3.21 or 7.4.2.12

Protein Sequence (257 amino acids)

>IAI47_06300 histidine ABC transporter ATP-binding protein HisP (Pantoea sp. MT58)
MADNKLSVTELHKRYGEHEVLKGVSLTAKAGDVISIIGSSGSGKSTFLRCINFLEKPSEG
SIMVNNQQITLVRDKDGQLKVADKEQLRALRTSLTMVFQHFNLWSHMTVLENVMEAPIQV
LGLSKAEARERAIRYLDKVGIDARAQAKYPVHLSGGQQQRVSIARALAMEPEVLLFDEPT
SALDPELVGEVLRIMQKLAEEGKTMVVVTHEMEFARHVSSHVIFLHQGKIEEQGPPAEVF
GNPKSPRLQQFLKGSLK