Protein Info for IAI47_05190 in Pantoea sp. MT58

Annotation: uracil permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 427 transmembrane" amino acids 20 to 38 (19 residues), see Phobius details amino acids 44 to 60 (17 residues), see Phobius details amino acids 67 to 84 (18 residues), see Phobius details amino acids 90 to 108 (19 residues), see Phobius details amino acids 120 to 145 (26 residues), see Phobius details amino acids 159 to 176 (18 residues), see Phobius details amino acids 183 to 205 (23 residues), see Phobius details amino acids 225 to 249 (25 residues), see Phobius details amino acids 267 to 281 (15 residues), see Phobius details amino acids 301 to 325 (25 residues), see Phobius details amino acids 331 to 354 (24 residues), see Phobius details amino acids 366 to 384 (19 residues), see Phobius details amino acids 391 to 412 (22 residues), see Phobius details TIGR00801: uracil-xanthine permease" amino acids 11 to 405 (395 residues), 430.4 bits, see alignment E=3.6e-133 PF00860: Xan_ur_permease" amino acids 16 to 382 (367 residues), 365.9 bits, see alignment E=1.1e-113

Best Hits

Swiss-Prot: 89% identical to URAA_ECOLI: Uracil permease (uraA) from Escherichia coli (strain K12)

KEGG orthology group: K02824, uracil permease (inferred from 100% identity to pva:Pvag_2251)

MetaCyc: 89% identical to uracil:H+ symporter UraA (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-132

Predicted SEED Role

"Uracil permease" in subsystem De Novo Pyrimidine Synthesis or Pyrimidine utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (427 amino acids)

>IAI47_05190 uracil permease (Pantoea sp. MT58)
MTRRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPILFHINPATVLLFNGVGTLIYLFI
CKGKIPAYLGSSFAFISPVLLLLPLGYEVALGGFILCGVLFCIVALIVKRAGTGWLDVMF
PPAAMGAIVAVIGLELAGVAANMAGLLPAEGSAPDSKTVLISLVTLAVTVFGSVLFRGFL
AIIPILVGVVAGYLLSAFMGIVDWSGVVKAPWFALPTFYTPRFEWVAMLTILPAALVVIA
EHIGHLVVTANIVKKDLIRDPGLHRSMFANGLSTVISGFFGSTPNTTYGENIGVMAITRV
YSTWVIGGAAILAILLSCVGKLAAVIQAIPVPVMGGVSLLLYGVIGASGIRVLIESKVDY
NKAQNLILTSVILIIGVSGAKLHIGAAELKGMALATIVGVGLALIFRVISLLRPEEVVLE
AEEPREQ