Protein Info for IAI47_04860 in Pantoea sp. MT58

Annotation: sigma-E factor regulatory protein RseB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 318 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF03888: MucB_RseB" amino acids 29 to 209 (181 residues), 198.7 bits, see alignment E=6.1e-63 PF17188: MucB_RseB_C" amino acids 221 to 312 (92 residues), 86.6 bits, see alignment E=1e-28

Best Hits

Swiss-Prot: 63% identical to RSEB_SHIFL: Sigma-E factor regulatory protein RseB (rseB) from Shigella flexneri

KEGG orthology group: K03598, sigma-E factor negative regulatory protein RseB (inferred from 98% identity to pva:Pvag_2319)

Predicted SEED Role

"Sigma factor RpoE negative regulatory protein RseB precursor" in subsystem Transcription initiation, bacterial sigma factors

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (318 amino acids)

>IAI47_04860 sigma-E factor regulatory protein RseB (Pantoea sp. MT58)
MKPLWYAVSLLTGSLLWSSAAPAQTTASGALLQQMEQASQNLNYEFAYINVSRIGIESLR
YRHAVIDNRIFAQLLQMDGPRREVIQRGNDISYFEPGLDPFSLPGNHIIDALPSVIFADF
TKLASAYDFITVGRSRIADQMCDVLRIVSRDGTRYSYVVWLDVDTKLPLRIDLLDRDGET
LEQFRVISFAVDEGVRNLMQGLEKANLPPSLSVPKGDAVTLTWQPGWIPAGMSLVSQNRR
TLPGLNKNMESKLYSDGLFSFAINVTPADKTSLTQTLRTGRRTVQTVVRNNNEIAVIGEL
PPSTAKRIADSIDLGSQK