Protein Info for IAI47_04360 in Pantoea sp. MT58

Annotation: HlyC/CorC family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 428 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 62 to 86 (25 residues), see Phobius details amino acids 92 to 112 (21 residues), see Phobius details amino acids 124 to 146 (23 residues), see Phobius details PF01595: CNNM" amino acids 11 to 182 (172 residues), 180 bits, see alignment E=5.6e-57 PF00571: CBS" amino acids 278 to 326 (49 residues), 27.2 bits, see alignment 6.2e-10 PF03471: CorC_HlyC" amino acids 344 to 418 (75 residues), 67.6 bits, see alignment E=1.2e-22

Best Hits

Swiss-Prot: 81% identical to YFJD_ECOLI: UPF0053 inner membrane protein YfjD (yfjD) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 95% identity to pva:Pvag_2392)

Predicted SEED Role

"Magnesium and cobalt efflux protein CorC" in subsystem Copper homeostasis: copper tolerance or Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (428 amino acids)

>IAI47_04360 HlyC/CorC family transporter (Pantoea sp. MT58)
MENVSTTTLIIILCIMVLVSAYFSGSETGMMTLNRYKLRHQAKNGDRAARRVEKLLRRPD
RLISLVLIGNNLVNILASALGTIVGMRLYGDAGVAIATGVLTFVVLVFAEVLPKTVAALY
PEKVAYPSSFLLTPLQYIMLPLVWLLNTITRLLMRLAGIRSDGSVNSALSKEELRTIVYE
SRSLMSRRNQDMLLSVLDLEKVSVDDIMVPRNEIVGININDDWKSVVRQLSHSPHGRIVL
FRDSLDDCVGMLRVREAWRMMTEKKEFTKETLLRAADEIYYIPEGTPLNTQLVKFQRNKE
KAGVVVDEYGDIKGLVTIEDILEEIVGDFTTSMSPSLAEEVMPQNDGSVLIEGSASVREI
NKAFNWDLPEQEARTINGMLLEALEEIPSIATRVQIGNYNVDILDVQDNMIKQVRITPKT
PLKKSVGS