Protein Info for IAI47_03300 in Pantoea sp. MT58

Annotation: EAL domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 949 TIGR00229: PAS domain S-box protein" amino acids 5 to 127 (123 residues), 56.4 bits, see alignment E=3.4e-19 amino acids 131 to 255 (125 residues), 69.8 bits, see alignment E=2.3e-23 amino acids 259 to 385 (127 residues), 71.4 bits, see alignment E=7.5e-24 amino acids 406 to 523 (118 residues), 26 bits, see alignment E=8.5e-10 PF00989: PAS" amino acids 12 to 119 (108 residues), 38.1 bits, see alignment E=5e-13 amino acids 136 to 241 (106 residues), 42.8 bits, see alignment E=1.6e-14 amino acids 264 to 374 (111 residues), 36.9 bits, see alignment E=1.1e-12 PF08448: PAS_4" amino acids 20 to 124 (105 residues), 28.3 bits, see alignment E=6.2e-10 amino acids 148 to 253 (106 residues), 33.5 bits, see alignment E=1.5e-11 amino acids 276 to 381 (106 residues), 32.6 bits, see alignment E=2.8e-11 PF13426: PAS_9" amino acids 20 to 121 (102 residues), 53.4 bits, see alignment E=9.8e-18 amino acids 148 to 250 (103 residues), 50.1 bits, see alignment E=9.9e-17 amino acids 276 to 378 (103 residues), 50.3 bits, see alignment E=8.5e-17 PF08447: PAS_3" amino acids 31 to 113 (83 residues), 33.5 bits, see alignment E=1.5e-11 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 527 to 690 (164 residues), 149.5 bits, see alignment E=7.3e-48 PF00990: GGDEF" amino acids 530 to 687 (158 residues), 172.7 bits, see alignment E=1.8e-54 PF00563: EAL" amino acids 707 to 938 (232 residues), 247.1 bits, see alignment E=5.7e-77

Best Hits

KEGG orthology group: None (inferred from 96% identity to pva:Pvag_2617)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (949 amino acids)

>IAI47_03300 EAL domain-containing protein (Pantoea sp. MT58)
MDNNSDVIYRMLVQSVIDYAITMLKPDGTVASWNGGGLHVLGYRPDEIIGQHATLFYNEE
DRRRGQLQRELDIAANAGRFETEGWRCRKDGSTFWAHVVIYPIRNEVARLVGFAAICRDC
TRQQEQQHKEREQESRFRLLVEGVTDYAIYMLDHDGNVVNWNAGAQRAKGYVAEEIVGQH
FSRFYSAQDRLNHVPEQNLQTAYRTGRFEDEGWRYRKDGSAFWAHVVIDTIRDDQGQLLG
YAKITRDCTEQQRIRSEQREQEQRFRLLVEGVTDYAIYMLDVDGVVVNWNAGAERAKGYK
AEEVVGQHFSLFYSSHERLNRTPEANLGIALKTGRFEDEGWRYRKDGSAFWAHVVIDAIH
DDDGKLVGFAKITRDRTERREQEQQILRARDLAEAQSTQKTALSKFLDNIIANIPSCVIV
EDAITREILLVNDRTQQLFGLSKSLIVNKRPHECMSPELSDYFNNLADVALRSEGMHERE
QLLMTASGERILHTRATAINGQDARRNYLMLLVEDVTDQRAADARIHHMAHHDNLTSLPN
RILFRQRLSEALRTAGQMQRQTAALCLDLDNFKNVNDALGHQIGDELLRSVAKRLRNALR
DQDTLARIGGDEFAIVLPHVAGNDEASAVAQRLIEAIRPPVNIEGHNLSVGLSVGIALST
TITNTPEQLLRCADMALYEAKRNGRNRYEHFTLEMDDVARSRRLIENDLRDAISGGHLRL
YYQPITNGDHHTIIGYEALMRWHHPIRGLIMPNDFIPIAEETGLIHMLGAFALYEACREA
ASWEGEQSVSVNLSPLQFKNSSLVPVVEGALKESGLDPARLEVEITESVLLDDSLGNIRT
LQNLKALGVQIALDDFGTGYSSLSYLRSFPFDKIKIDKSFINDMGDSREALAIIRAITGM
SRSLDIQITAEGVESDEQFAKLRDEGCTLFQGFLFGRPQPSELRLKTLG