Protein Info for IAI47_02845 in Pantoea sp. MT58

Annotation: penicillin-binding protein activator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 680 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF04348: LppC" amino acids 41 to 288 (248 residues), 148.9 bits, see alignment E=1.2e-47 amino acids 349 to 674 (326 residues), 311.4 bits, see alignment E=6.9e-97

Best Hits

Swiss-Prot: 77% identical to LPOA_PANAM: Penicillin-binding protein activator LpoA (lpoA) from Pantoea ananatis (strain LMG 20103)

KEGG orthology group: K07121, (no description) (inferred from 96% identity to pva:Pvag_2738)

MetaCyc: 56% identical to outer membrane lipoprotein - activator of MrcA activity (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"LppC putative lipoprotein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (680 amino acids)

>IAI47_02845 penicillin-binding protein activator (Pantoea sp. MT58)
MLPSKVVRHKAGRFLPVILAGLILAACSGQAPQTSTVNIQGPATASSAYYLQQAQQSSDD
SKTDWQLLAIRALLKEGKYPEATQQLSQLPQQLSETQQQESLLLKAQLLIAQQKTKDAEP
LLAAVKTSALSQDQLARYYSLQIASAQGRPSLSLLRNYIAQEPLLKDADHQSNIDATWQT
LTQMSPQEASNLVINADENVLQGWLDLLAVWRANAQDAEMLKSGIKDWQTRYPQNPAAKT
LPTQLSQMQNYTKASTSIIALLLPLNGQAQVFANAIQKGFNDAKNGVSAPVAQPAAATAQ
PAAADATASAQPAAAAGSSADPISAPQQSATTTPQQQPQSQPQSQPAAAAPASNAQIKVY
DTSSQPIEQVMQQAQQDGATIVVGPLLKSNVEKVANSQTPLNVLALNEPEKIQNHPNICY
FALSPEDEARDAAHHIWDQGKRQPLLLVPRSGLGDRVTNAFAQEWQTLGGSTVMQQRFGS
TAELKQGINSGAGISLSGTPVNAAPAEPQGVSIAGLTIPAPQQSTPDVVSTSSGGGIDAV
YIVSTQDELQLIKPMITMRTGSRSNISLYASSRSAQAGAGPDFRLEMDGLQFSDIPLLSG
SNPGLMQQTSKSFNNDYSLVRLYAMGMDAWTLANHFNQMRQSPGFTLDGNTGKLSADTDC
VINRKLTWNQYRRGEIAPAN